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冬季室温对动态血压的影响:一项随机对照研究。

Influence of room heating on ambulatory blood pressure in winter: a randomised controlled study.

机构信息

Department of Community Health and Epidemiology, Nara Medical University School of Medicine, 840 Shijocho, Kashiharashi, Nara 634-8521, Japan.

出版信息

J Epidemiol Community Health. 2013 Jun;67(6):484-90. doi: 10.1136/jech-2012-201883. Epub 2013 Feb 27.

Abstract

BACKGROUND

Previous studies have proposed that higher blood pressure (BP) in winter is an important cause of increased mortality from cardiovascular disease during the winter. Some observational and physiological studies have shown that cold exposure increases BP, but evidence from a randomised controlled study assessing the effectiveness of intensive room heating for lowering BP was lacking.

OBJECTIVES

The present study aimed to determine whether intensive room heating in winter decreases ambulatory BP as compared with weak room heating resulting in a 10°C lower target room temperature when sufficient clothing and bedclothes are available.

METHODS

We conducted a parallel group, assessor blinded, simple randomised controlled study with 1:1 allocation among 146 healthy participants in Japan from November 2009 to March 2010. Ambulatory BP was measured while the participants stayed in single experimental rooms from 21:00 to 8:00. During the session, participants could adjust the amount of clothing and bedclothes as required. Compared with the weak room heating group (mean temperature ± SD: 13.9 ± 3.3°C), systolic morning BP (mean BP 2 h after getting out of bed) of the intensive room heating group (24.2 ± 1.7°C) was significantly lower by 5.8 mm Hg (95% CI 2.4 to 9.3). Sleep-trough morning BP surges (morning BP minus lowest night-time BP) in the intensive room heating group were significantly suppressed to about two thirds of the values in the weak room heating group (14.3 vs 21.9 mm Hg; p<0.01).

CONCLUSIONS

Intensive room heating decreased morning BP and the morning BP surge in winter.

摘要

背景

先前的研究表明,冬季血压升高是心血管疾病冬季死亡率增加的一个重要原因。一些观察性和生理学研究表明,寒冷暴露会升高血压,但缺乏关于强化室内供暖降低血压的随机对照研究的证据。

目的

本研究旨在确定在冬季,与弱室内供暖相比,强化室内供暖是否会降低动态血压,弱室内供暖导致目标室内温度降低 10°C,同时保证有足够的衣物和床上用品。

方法

我们在日本进行了一项平行组、评估者设盲、简单随机对照研究,于 2009 年 11 月至 2010 年 3 月期间纳入 146 名健康参与者,采用 1:1 随机分组。参与者在单人实验室内从 21:00 到 8:00 期间佩戴动态血压监测仪。在这段时间内,参与者可以根据需要调整衣物和床上用品的数量。与弱室内供暖组(平均温度±标准差:13.9±3.3°C)相比,强化室内供暖组(24.2±1.7°C)的清晨收缩压(起床后 2 小时的平均血压)显著降低 5.8mmHg(95%CI 2.4 至 9.3)。强化室内供暖组的睡眠中清晨血压骤升(清晨血压减去最低夜间血压)显著降低至弱室内供暖组的三分之二左右(14.3 对 21.9mmHg;p<0.01)。

结论

强化室内供暖可降低冬季清晨血压和清晨血压骤升。

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