Saeki Keigo, Obayashi Kenji, Iwamoto Junko, Tone Nobuhiro, Okamoto Nozomi, Tomioka Kimiko, Kurumatani Norio
aDepartment of Community Health and Epidemiology, Nara Medical University School of Medicine bDepartment of Nursing, Tenri Healthcare University cCenter for Academic Industrial and Governmental Relations, Nara Medical University School of Medicine, Nara, Japan.
J Hypertens. 2014 Aug;32(8):1582-9. doi: 10.1097/HJH.0000000000000232.
Higher cardiovascular mortality in winter may be partly explained by increased blood pressure (BP) because of cold exposure. However, this winter excess mortality is higher in countries with moderate winter than those with severe winter climate.
Although higher BP in low outdoor temperatures has been reported, the magnitude of association of indoor temperature with ambulatory BP remained unclear. We aimed to compare the associations of indoor and outdoor temperature with ambulatory BP.
From repeated measurements on two consecutive days during colder months (October-April) among 868 elderly individuals, we assessed the association of indoor and outdoor temperatures with ambulatory BP using multilevel analysis with random intercept for each individual.
Correlation between indoor and outdoor temperature got weak along with decreasing outdoor temperature. Outdoor temperature was not significantly associated with ambulatory BP. In contrast, a 1°C lower indoor temperature was significantly associated with 0.22 mmHg higher daytime SBP, 0.18% higher nocturnal BP fall, 0.34 mmHg higher sleep-trough morning BP surge independent of potential confounders including physical activity. The models with indoor temperature showed better fit of the model than those with outdoor temperature. Night-time SBP did not show significant association with indoor and outdoor temperature but with bed temperature.
Our results suggest the importance to assess the association of indoor temperature with cardiovascular mortality to determine whether improving housing thermal environment reduces winter excess mortality.
Indoor temperature showed stronger association than outdoor temperature with BP in colder months.
冬季心血管死亡率较高可能部分归因于寒冷暴露导致的血压升高。然而,在冬季气候温和的国家,这种冬季额外死亡率高于冬季气候严寒的国家。
尽管已有报道称在低室外温度下血压会升高,但室内温度与动态血压之间的关联程度仍不明确。我们旨在比较室内和室外温度与动态血压之间的关联。
在868名老年人较寒冷月份(10月至4月)连续两天的重复测量中,我们使用对每个个体进行随机截距的多水平分析,评估室内和室外温度与动态血压之间的关联。
随着室外温度降低,室内和室外温度之间的相关性减弱。室外温度与动态血压无显著关联。相比之下,室内温度每降低1°C,日间收缩压显著升高0.22 mmHg,夜间血压降幅升高0.18%,睡眠低谷期晨起血压激增升高0.34 mmHg,且不受包括身体活动在内的潜在混杂因素影响。包含室内温度的模型比包含室外温度的模型拟合度更好。夜间收缩压与室内和室外温度无显著关联,但与床温有关。
我们的结果表明,评估室内温度与心血管死亡率之间的关联对于确定改善居住热环境是否能降低冬季额外死亡率具有重要意义。
在较寒冷月份,室内温度与血压的关联比室外温度更强。