加拿大的生殖器疱疹：解读隐藏的疫情。
Genital herpes in Canada: Deciphering the hidden epidemic.
机构信息
Department of Epidemiology and Community Medicine, University of Ottawa;
出版信息
Can J Infect Dis Med Microbiol. 2012 Spring;23(1):e6-9. doi: 10.1155/2012/386329.
INTRODUCTION
Genital herpes (GH) is the most common cause of genital ulceration, but is not reportable in Canada. Research in the United States has found that less than 10% of seropositive persons reported a diagnosis of GH. The present article investigates the rates of diagnosed cases of GH in Canada from 2002 to 2007.
METHODS
Primary case diagnosis data on GH for the period between 2002 and 2007 were obtained from the Canadian Disease and Therapeutic Index, a proprietary database maintained by Intercontinental Medical Statistics (IMS) Health Canada. Of the 45,000 to 49,000 office-based physicians in Canada, IMS Health collected diagnosis-specific prescription diaries from a sample of 652, stratified according to geographic region and representing all major specialties, during this period.
RESULTS
Between 2002 and 2007, there were approximately 84,398 to 122,456 medically attended GH cases annually in Canada. Approximately 74% to 93% of these diagnosed cases made one physician visit per year. The annual rate of medically attended GH cases ranged from 261.2 per 100,000 population to 386.6 per 100,000 population.
DISCUSSION
The present report is the first time that administrative data have been used to estimate the annual rate of medically attended GH cases in Canada. The data include both incident and prevalent cases and are likely an underestimate of the actual number of cases because they only represent diagnosed cases presenting for medical care. Further seroepidemiological and clinical research studies would be helpful to assess the burden of infection and to plan appropriate diagnostic, treatment and preventive counselling services.
INTRODUCTION
Genital herpes (GH) is the most common cause of genital ulceration, but is not reportable in Canada. Research in the United States has found that less than 10% of seropositive persons reported a diagnosis of GH. The present article investigates the rates of diagnosed cases of GH in Canada from 2002 to 2007.
METHODS
Primary case diagnosis data on GH for the period between 2002 and 2007 were obtained from the Canadian Disease and Therapeutic Index, a proprietary database maintained by Intercontinental Medical Statistics (IMS) Health Canada. Of the 45,000 to 49,000 office-based physicians in Canada, IMS Health collected diagnosis-specific prescription diaries from a sample of 652, stratified according to geographic region and representing all major specialties, during this period.
RESULTS
Between 2002 and 2007, there were approximately 84,398 to 122,456 medically attended GH cases annually in Canada. Approximately 74% to 93% of these diagnosed cases made one physician visit per year. The annual rate of medically attended GH cases ranged from 261.2 per 100,000 population to 386.6 per 100,000 population.
DISCUSSION
The present report is the first time that administrative data have been used to estimate the annual rate of medically attended GH cases in Canada. The data include both incident and prevalent cases and are likely an underestimate of the actual number of cases because they only represent diagnosed cases presenting for medical care. Further seroepidemiological and clinical research studies would be helpful to assess the burden of infection and to plan appropriate diagnostic, treatment and preventive counselling services.
简介
生殖器疱疹（GH）是生殖器溃疡最常见的原因，但在加拿大不需要报告。美国的研究发现，不到 10%的血清阳性者报告过 GH 的诊断。本文调查了 2002 年至 2007 年期间加拿大 GH 确诊病例的发病率。
方法
2002 年至 2007 年期间的 GH 主要病例诊断数据来自加拿大疾病和治疗索引，这是 Intercontinental Medical Statistics（IMS）健康加拿大公司维护的专有数据库。IMS 健康从加拿大 45000 到 49000 名门诊医生中，在这段时间内，按照地理位置和代表所有主要专业的分层，从 652 名医生中收集了特定诊断的处方日记。
结果
2002 年至 2007 年期间，加拿大每年约有 84398 至 122456 例医学上治疗的 GH 病例。这些确诊病例中，约有 74%至 93%的人每年看一次医生。每年接受医学治疗的 GH 病例发病率从每 10 万人 261.2 例到每 10 万人 386.6 例不等。
讨论
本报告首次使用行政数据估计加拿大每年接受医学治疗的 GH 病例的发病率。这些数据包括新发病例和现患病例，并且由于它们仅代表接受医疗保健的确诊病例，因此可能低估了实际病例数。进一步的血清流行病学和临床研究将有助于评估感染负担，并规划适当的诊断、治疗和预防咨询服务。
Zotero 插件