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成人髋关节囊外骨折的髓外固定植入物及外固定器

Extramedullary fixation implants and external fixators for extracapsular hip fractures in adults.

作者信息

Parker Martyn J, Das Avishek

机构信息

Department of Orthopaedics, Peterborough and Stamford Hospitals NHS Foundation Trust, Peterborough, UK.

出版信息

Cochrane Database Syst Rev. 2013 Feb 28;2013(2):CD000339. doi: 10.1002/14651858.CD000339.pub3.

Abstract

BACKGROUND

Extramedullary fixation of hip fractures involves the application of a plate and screws to the lateral side of the proximal femur. In external fixators, the stabilising component is held outside the thigh by pins or screws driven into the bone. This is an update of a Cochrane review first published in 1998, and last updated in 2005.

OBJECTIVES

To assess the relative effects of different types of extramedullary fixation implant, as well as external fixators, for treating extracapsular proximal femoral (hip) fractures in adults.

SEARCH METHODS

We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (July 2011), the Cochrane Central Register of Controlled Trials (The Cochrane Library 2011, Issue 2), MEDLINE (1966 to June Week 4 2011), EMBASE (1988 to 2011 Week 25), various other databases, conference proceedings and reference lists.

SELECTION CRITERIA

Randomised or quasi-randomised controlled trials comparing extramedullary implants or external fixators for fixing extracapsular hip fracture in adults were included.

DATA COLLECTION AND ANALYSIS

Two review authors independently selected trials, assessed risk of bias and extracted data. Data were pooled where appropriate.

MAIN RESULTS

The 18 included trials tested seven comparisons in a total of 2615 mainly female and older participants with a total of 2619 fractures. All trials had methodological flaws that may affect the validity of their results.Three trials of 355 participants comparing a fixed nail plate (Jewett or McLaughlin) with the sliding hip screw (SHS) found an increased risk of fixation failure for fixed nail plates.The two trials of 433 participants comparing the Resistance Augmented Bateaux (RAB) plate with the SHS had contrasting results, notably in terms of operative complications, fixation failure and anatomical restoration.One trial of 100 participants comparing the Pugh nail and the SHS found no significant difference between implants.Three trials of 458 participants compared the Medoff plate with the SHS. There was a trend to higher blood losses and longer operation times for the Medoff plate along with a trend to a lower risk of fixation failure with the Medoff plate for unstable trochanteric fractures.Two trials of 676 participants compared the Medoff plate with three different screw-plate systems. There were no statistically significant differences in outcome for trochanteric fractures. For subtrochanteric fractures, there was a lower fixation failure rate for the Medoff plate but no evidence for differences in longer-term outcomes.Four trials of 396 participants comparing the Gotfried percutaneous compression plate (PCCP) with a SHS found a trend to lower blood loss and transfusion requirements for the PCCP but no other confirmed differences in outcomes between implants. Three of the trials reported intra-operative problems with the PCCP, some of which precluded its use.Three trials of 200 participants comparing external fixation with a SHS found less operative trauma for the external fixation. Final outcome appeared similar.

AUTHORS' CONCLUSIONS: The markedly increased fixation failure rate of fixed nail plates compared with the SHS is a major consideration and thus the SHS appears preferable.There was insufficient evidence from other comparisons of extramedullary implants or on the use of external fixators to draw definite conclusions.

摘要

背景

髋部骨折的髓外固定是指在股骨近端外侧应用钢板和螺钉。在外部固定器中,稳定部件通过打入骨头的钢针或螺钉固定在大腿外侧。这是Cochrane系统评价的更新版,该评价首次发表于1998年,上次更新于2005年。

目的

评估不同类型的髓外固定植入物以及外部固定器治疗成人股骨近端(髋部)囊外骨折的相对疗效。

检索方法

我们检索了Cochrane骨、关节与肌肉创伤组专业注册库(2011年7月)、Cochrane对照试验中心注册库(《Cochrane图书馆》2011年第2期)、MEDLINE(1966年至2011年第4周)、EMBASE(1988年至2011年第25周)、其他多个数据库、会议论文集及参考文献列表。

选择标准

纳入比较髓外植入物或外部固定器治疗成人股骨近端囊外骨折的随机或半随机对照试验。

数据收集与分析

两位综述作者独立选择试验、评估偏倚风险并提取数据。在适当情况下对数据进行合并。

主要结果

纳入的18项试验共对7组比较进行了测试,涉及2615名主要为女性且年龄较大的参与者,共计2619处骨折。所有试验均存在方法学缺陷,可能影响结果的有效性。三项涉及355名参与者的试验比较了固定钉板(Jewett或McLaughlin)与滑动髋螺钉(SHS),发现固定钉板的固定失败风险增加。两项涉及433名参与者的试验比较了增强抗力型Bateaux(RAB)钢板与SHS,结果相互矛盾,尤其是在手术并发症、固定失败及解剖复位方面。一项涉及100名参与者的试验比较了Pugh钉与SHS,发现两种植入物之间无显著差异。三项涉及458名参与者的试验比较了Medoff钢板与SHS。Medoff钢板有失血更多、手术时间更长的趋势,且对于不稳定转子间骨折,其固定失败风险有降低趋势。两项涉及676名参与者的试验比较了Medoff钢板与三种不同的螺钉钢板系统。转子间骨折的结局无统计学显著差异。对于转子下骨折,Medoff钢板的固定失败率较低,但无证据表明长期结局存在差异。四项涉及396名参与者的试验比较了Gotfried经皮加压钢板(PCCP)与SHS,发现PCCP有失血和输血需求降低的趋势,但植入物之间在其他结局方面无其他确认差异。三项试验报告了PCCP的术中问题,其中一些问题使其无法使用。三项涉及200名参与者的试验比较了外固定与SHS,发现外固定的手术创伤较小。最终结局似乎相似。

作者结论

与SHS相比,固定钉板的固定失败率显著增加是一个主要考量因素,因此SHS似乎更可取。关于髓外植入物的其他比较或外部固定器的使用,证据不足,无法得出明确结论。

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