2012 年朝觐期间，法国朝觐者返回后，新型冠状病毒（HCoV-EMC）在鼻腔中并未携带，尽管呼吸道症状发生率很高。
Lack of nasal carriage of novel corona virus (HCoV-EMC) in French Hajj pilgrims returning from the Hajj 2012, despite a high rate of respiratory symptoms.
机构信息
IHU Méditerranée Infection, APHM Public Hospitals of Marseille, Marseille, France.
出版信息
Clin Microbiol Infect. 2013 Jul;19(7):E315-7. doi: 10.1111/1469-0691.12174. Epub 2013 Mar 2.
Abstract
A cohort of 154 French Hajj pilgrims participating in the 2012 Hajj were systematically sampled with nasal swabs prior to returning to France, and screened for the novel HCoV-EMC coronavirus by two real-time RT-PCR assays. Despite a high rate of respiratory symptoms (83.4%), including 41.0% influenza-like illness, no case of HCoV-EMC infection was detected. Despite the fact that zoonotic transmission was suspected in the first few cases, a recent family cluster in the Kingdom of Saudi Arabia suggests that the virus might show at least limited spread from person to person, which justifies continuing epidemiological surveillance.
摘要
154 名法国朝觐者组成的队列在返回法国前，通过鼻腔拭子被系统性采样，使用两种实时 RT-PCR 检测方法筛查新型 HCoV-EMC 冠状病毒。尽管有很高的呼吸道症状发生率（83.4%），包括 41.0%的流感样疾病，但未检测到 HCoV-EMC 感染病例。尽管在最初的几例病例中怀疑存在人畜共患传播，但沙特阿拉伯王国最近的一个家庭聚集性病例表明，该病毒至少可能在人与人之间有限传播，这证明有必要继续进行流行病学监测。
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