Department of Clinical Sciences, Lund University, CRC, Bldg. 60:11, Jan Waldenströms gata 35, SE 20502 Malmö, Sweden.
Public Health Nutr. 2013 Aug;16(8):1390-402. doi: 10.1017/S1368980013000293. Epub 2013 Mar 4.
The aim of the present study was to examine the prevalence and associated factors of dietary supplement use, particularly supplements containing vitamin D and fatty acids, in pregnant women enrolled in a multi-national study.
The Environmental Determinants of Diabetes in the Young (TEDDY) study is a prospective longitudinal cohort study. Maternal dietary supplement use was self-reported through questionnaires at month 3 to 4 postpartum.
Six clinical research centres; three in the USA (Colorado, Georgia/Florida and Washington) and three in Europe (Sweden, Finland and Germany).
Mothers (n 7326) to infants screened for high-risk HLA-DQ genotypes of type 1 diabetes.
Ninety-two per cent of the 7326 women used one or more types of supplement during pregnancy. Vitamin D supplements were taken by 65% of the women, with the highest proportion of users in the USA (80.5 %). Overall, 16% of the women reported taking fatty acid supplements and a growing trend was seen in all countries between 2004 and 2010 (P,0.0001). The use was more common in Germany (32 %) and the USA (24 %) compared with Finland (8.5%) and Sweden (7.0 %). Being pregnant with the first child was a strong predictor for any supplement use in all countries. Low maternal age (<25 years), higher education, BMI<=25.0 kg/m2 and smoking during pregnancy were factors associated with supplement use in some but not all countries.
The majority of the women used dietary supplements during pregnancy. The use was associated with sociodemographic and behavioural factors, such as parity, maternal age, education, BMI and maternal smoking.
本研究旨在调查参与多国研究的孕妇使用膳食补充剂(尤其是含维生素 D 和脂肪酸的补充剂)的流行情况及其相关因素。
环境因素与青少年 1 型糖尿病研究(TEDDY)是一项前瞻性纵向队列研究。产妇膳食补充剂的使用情况通过产后 3 至 4 个月的问卷进行自我报告。
6 个临床研究中心;美国 3 个(科罗拉多州、乔治亚州/佛罗里达州和华盛顿州),欧洲 3 个(瑞典、芬兰和德国)。
接受高危 HLA-DQ 基因型 1 型糖尿病筛查的婴儿的母亲(n=7326)。
7326 名女性中有 92%在孕期使用了一种或多种类型的补充剂。65%的女性服用维生素 D 补充剂,其中美国的使用者比例最高(80.5%)。总体而言,16%的女性报告服用脂肪酸补充剂,2004 年至 2010 年间所有国家的服用趋势呈上升趋势(P<0.0001)。德国(32%)和美国(24%)的使用率高于芬兰(8.5%)和瑞典(7.0%)。在所有国家中,首次怀孕是使用任何补充剂的强有力预测因素。产妇年龄较低(<25 岁)、受教育程度较高、BMI≤25.0kg/m2 和孕期吸烟是一些国家而非所有国家补充剂使用的相关因素。
大多数女性在孕期使用膳食补充剂。使用情况与社会人口统计学和行为因素相关,如产次、产妇年龄、教育程度、BMI 和产妇吸烟。