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翅荚决明叶提取物和山奈酚3 - O -槐糖苷的镇痛活性。

Analgesic activity of Cassia alata leaf extract and kaempferol 3-o-sophoroside.

作者信息

Palanichamy S, Nagarajan S

机构信息

Department of Pharmacology, Thanjavur Medical College, India.

出版信息

J Ethnopharmacol. 1990 Apr;29(1):73-8. doi: 10.1016/0378-8741(90)90099-f.

DOI:10.1016/0378-8741(90)90099-f
PMID:2345462
Abstract

The analgesic activity of an extract of the leaves of Cassia alata and kaempferol 3-O-sophoroside were studied after intraperitoneal injection in mice and rats using the tail clip, tail flick, tail immersion and acetic acid-induced writhing methods and the results compared with morphine. Maximum analgesic activity of the extract was apparent 120 min after injection. Fifty milligrams of kaempferol 3-O-sophoroside appeared equivalent to 100 mg of the extract.

摘要

采用尾夹法、尾尖甩动法、尾浸法和醋酸诱导扭体法,对翅荚决明叶提取物和山柰酚3-O-槐糖苷腹腔注射小鼠和大鼠后的镇痛活性进行了研究,并将结果与吗啡进行比较。提取物的最大镇痛活性在注射后120分钟出现。50毫克山柰酚3-O-槐糖苷的镇痛效果似乎与100毫克提取物相当。

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