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山茱萸果实中的亲脂性成分及其抗肿瘤活性。

Lipophilic components from Fructus Viticis Negundo and their anti-tumor activities.

机构信息

School of Pharmaceutical Sciences, Central South University, Changsha 410000, China.

出版信息

Fitoterapia. 2013 Apr;86:144-8. doi: 10.1016/j.fitote.2013.02.009. Epub 2013 Feb 27.

Abstract

Two new triterpenoids, (24R/S)-24-hydroxy-3α 10α-epoxy-9-eip-cucurbita-25-ene (1a, b), as well as six known compounds (3-8), were isolated from the extraction of Fructus Viticis Negundo. Their structures were established on the basis of spectral analysis. In addition, all the compounds were tested for inhibitory effect against K-562 and A-549 cell lines.

摘要

从乌蔹莓果实的提取物中分离得到了两种新的三萜类化合物(24R/S)-24-羟基-3α10α-环氧-9-表齐墩果-25-烯(1a,b),以及六种已知化合物(3-8)。根据光谱分析确定了它们的结构。此外,还测试了所有化合物对 K-562 和 A-549 细胞系的抑制作用。

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