Xing W J, Zhang Z L
Department of Biology, Nankai University, Tianjin, China.
Mutat Res. 1990 Jun;241(2):109-13. doi: 10.1016/0165-1218(90)90113-g.
A comparison of the Vicia faba SCE with the human lymphocyte SCE test was made with regard to their capacity to detect mutagens. Twelve chemical agents that can induce sister-chromatid exchanges (SCEs) in both Vicia faba root tip cells and human lymphocytes were used. The results indicate that the plant SCE technique is a sensitive test for screening various chemical agents including food preservatives, pesticides and essences which may have mutagenic activity. A new simplified procedure was introduced for differential staining of sister chromatids in Vicia faba.
就检测诱变剂的能力而言，对蚕豆姐妹染色单体互换（SCE）与人类淋巴细胞SCE试验进行了比较。使用了12种能在蚕豆根尖细胞和人类淋巴细胞中诱导姐妹染色单体互换（SCE）的化学试剂。结果表明，植物SCE技术是一种用于筛选各种可能具有诱变活性的化学试剂的灵敏试验，这些化学试剂包括食品防腐剂、农药和香精。引入了一种新的简化程序用于蚕豆姐妹染色单体的鉴别染色。
