1986 - 1988年剑桥郡人类呼吸道衣原体感染研究。
A study of human respiratory tract chlamydial infections in Cambridgeshire 1986-88.
作者信息
Wreghitt T G, Barker C E, Treharne J D, Phipps J M, Robinson V, Buttery R B
机构信息
Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge.
出版信息
Epidemiol Infect. 1990 Jun;104(3):479-88. doi: 10.1017/s0950268800047488.
Human respiratory tract chlamydial infections have been studied in Cambridgeshire for many years, but until recently we have been unable to distinguish between infection with Chlamydia psittaci or Chlamydia pneumoniae (TWAR). In this study, we have employed the micro-immunofluorescence (micro-IF) test for this purpose and to look for the relative incidence of C. psittaci and C. pneumoniae infections in Cambridgeshire. Among 50 patients with community-acquired respiratory tract symptoms whose serum samples had Chlamydia complement fixation test titres greater than or equal to 64, 25 had evidence of recent C. psittaci or C. pneumoniae infection. Nineteen (76%) of the 25 patients had evidence of recent C. psittaci infection and of these 16 (84%) had recently had contact with birds. Six patients (24%) had evidence of recent C. pneumoniae infection, and of these, only two (33%) had recently had contact with birds. While C. psittaci was grown from several of the birds associated with human C. psittaci infection, it was not cultured from any of the birds in contact with the two human C. pneumoniae cases.
在剑桥郡，对人类呼吸道衣原体感染的研究已开展多年，但直到最近，我们仍无法区分鹦鹉热衣原体感染和肺炎衣原体（TWAR）感染。在本研究中，我们采用微量免疫荧光（micro-IF）试验来实现这一目的，并探寻剑桥郡鹦鹉热衣原体和肺炎衣原体感染的相对发病率。在50名社区获得性呼吸道症状患者中，其血清样本衣原体补体结合试验滴度大于或等于64，其中25人有近期鹦鹉热衣原体或肺炎衣原体感染的证据。这25名患者中有19人（76%）有近期鹦鹉热衣原体感染的证据，其中16人（84%）近期接触过鸟类。6名患者（24%）有近期肺炎衣原体感染的证据，其中只有2人（33%）近期接触过鸟类。虽然从几例与人类鹦鹉热衣原体感染相关的鸟类中培养出了鹦鹉热衣原体，但在与两例人类肺炎衣原体病例接触的鸟类中均未培养出该病原体。
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