College of Veterinary Medicine, National Reference Laboratory of Veterinary Drug Residues, SCAU, South China Agricultural University, Guangzhou, China.
Antimicrob Agents Chemother. 2013 Jun;57(6):2824-7. doi: 10.1128/AAC.02155-12. Epub 2013 Mar 11.
pHN1122-1 carrying bla(CTX-M-55), from an Escherichia coli isolate from a dog, was completely sequenced. pHN1122-1 has an IncI2 replicon and typical IncI2-associated genetic modules, including mok/hok-finO-yafA/B, nikABC, and two transfer regions, tra and pil, as well as a shufflon. bla(CTX-M-55) is found within a 3.084-kb ISEcp1 transposition unit that includes a fragment of IncA/C plasmid backbone. pHN1122-1 and closely related plasmids were identified in other E. coli isolates from animals in China.
pHN1122-1 携带 bla(CTX-M-55)，该基因源自一只狗体内分离出的大肠杆菌，其已完成全序列测定。pHN1122-1 带有 IncI2 复制子，以及典型的 IncI2 相关遗传模块，包括 mok/hok-finO-yafA/B、nikABC 和两个转移区 tra 和 pil，还有一个 shufflon。bla(CTX-M-55)位于一个 3.084kb 的 ISEcp1 转座单元内，该单元包含 IncA/C 质粒骨架的一个片段。pHN1122-1 及其密切相关的质粒在中国的动物来源大肠杆菌中被发现。
