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在中国,宠物和食用动物中携带 blaCTX-M-55 的 IncI2 质粒的遗传特征。

Genetic characterization of IncI2 plasmids carrying blaCTX-M-55 spreading in both pets and food animals in China.

机构信息

College of Veterinary Medicine, National Reference Laboratory of Veterinary Drug Residues, SCAU, South China Agricultural University, Guangzhou, China.

出版信息

Antimicrob Agents Chemother. 2013 Jun;57(6):2824-7. doi: 10.1128/AAC.02155-12. Epub 2013 Mar 11.

Abstract

pHN1122-1 carrying bla(CTX-M-55), from an Escherichia coli isolate from a dog, was completely sequenced. pHN1122-1 has an IncI2 replicon and typical IncI2-associated genetic modules, including mok/hok-finO-yafA/B, nikABC, and two transfer regions, tra and pil, as well as a shufflon. bla(CTX-M-55) is found within a 3.084-kb ISEcp1 transposition unit that includes a fragment of IncA/C plasmid backbone. pHN1122-1 and closely related plasmids were identified in other E. coli isolates from animals in China.

摘要

pHN1122-1 携带 bla(CTX-M-55),该基因源自一只狗体内分离出的大肠杆菌,其已完成全序列测定。pHN1122-1 带有 IncI2 复制子,以及典型的 IncI2 相关遗传模块,包括 mok/hok-finO-yafA/B、nikABC 和两个转移区 tra 和 pil,还有一个 shufflon。bla(CTX-M-55)位于一个 3.084kb 的 ISEcp1 转座单元内,该单元包含 IncA/C 质粒骨架的一个片段。pHN1122-1 及其密切相关的质粒在中国的动物来源大肠杆菌中被发现。

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