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脉氧仪:了解其基本原理有助于认识其局限性。

Pulse oximetry: understanding its basic principles facilitates appreciation of its limitations.

机构信息

Denver Veterans Affairs Medical Center, USA.

出版信息

Respir Med. 2013 Jun;107(6):789-99. doi: 10.1016/j.rmed.2013.02.004. Epub 2013 Mar 13.

DOI:10.1016/j.rmed.2013.02.004
PMID:23490227
Abstract

Pulse oximetry has revolutionized the ability to monitor oxygenation in a continuous, accurate, and non-invasive fashion. Despite its ubiquitous use, it is our impression and supported by studies that many providers do not know the basic principles behind its mechanism of function. This knowledge is important because it provides the conceptual basis of appreciating its limitations and recognizing when pulse oximeter readings may be erroneous. In this review, we discuss how pulse oximeters are able to distinguish oxygenated hemoglobin from deoxygenated hemoglobin and how they are able to recognize oxygen saturation only from the arterial compartment of blood. Based on these principles, we discuss the various conditions that can cause spurious readings and the mechanisms underlying them.

摘要

脉搏血氧仪的出现彻底改变了连续、准确、无创监测氧合的能力。尽管它的应用非常广泛,但我们的印象以及相关研究也表明,许多医务人员并不了解其工作机制背后的基本原理。这些知识非常重要,因为它为理解脉搏血氧仪的局限性以及认识到何时可能会出现错误读数提供了概念基础。在这篇综述中,我们将讨论脉搏血氧仪如何区分氧合血红蛋白和去氧血红蛋白,以及它们如何仅从血液的动脉部分识别氧饱和度。基于这些原理,我们将讨论可能导致错误读数的各种情况及其背后的机制。

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1
Pulse oximetry: understanding its basic principles facilitates appreciation of its limitations.脉氧仪:了解其基本原理有助于认识其局限性。
Respir Med. 2013 Jun;107(6):789-99. doi: 10.1016/j.rmed.2013.02.004. Epub 2013 Mar 13.
2
Pulse oximetry: an alternative method for the assessment of oxygenation in newborn infants.脉搏血氧饱和度测定法:评估新生儿氧合的一种替代方法。
Pediatrics. 1987 Apr;79(4):524-8.
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Continuous monitoring of fetal oxygen saturation by pulse oximetry.通过脉搏血氧饱和度仪持续监测胎儿血氧饱和度。
Obstet Gynecol. 1995 Feb;85(2):183-6. doi: 10.1016/0029-7844(94)00353-F.
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Notes on the apparent discordance of pulse oximetry and multi-wavelength haemoglobin photometry.关于脉搏血氧饱和度测定法与多波长血红蛋白光度测定法明显不一致的说明。
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Pulse oximetry in very low birth weight infants with acute and chronic lung disease.极低出生体重儿急性和慢性肺部疾病的脉搏血氧饱和度测定
Pediatrics. 1987 Apr;79(4):612-7.
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Variations in optical absorption spectra of adult and fetal hemoglobins and its effect on pulse oximetry.成人和胎儿血红蛋白光吸收光谱的变化及其对脉搏血氧饱和度测定的影响。
IEEE Trans Biomed Eng. 1989 Aug;36(8):844-8. doi: 10.1109/10.30810.
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Pulse oximetry in mixed haemoglobinopathy.混合性血红蛋白病中的脉搏血氧饱和度测定法。
Anaesth Intensive Care. 1996 Oct;24(5):619-20.
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Dyshemoglobinemias and pulse oximetry: a therapeutic challenge.血红蛋白异常血症与脉搏血氧饱和度测定:一项治疗挑战。
J Pediatr Hematol Oncol. 2008 Nov;30(11):850-2. doi: 10.1097/MPH.0b013e31817e4a19.
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From oxygen content to pulse oximetry: completing the picture in the newborn.从氧含量到脉搏血氧饱和度测定:完善新生儿的情况评估
Acta Anaesthesiol Scand Suppl. 1995;107:95-100. doi: 10.1111/j.1399-6576.1995.tb04341.x.
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Absorption characteristics of human fetal hemoglobin at wavelengths used in pulse oximetry.脉搏血氧饱和度测定中使用波长下的人胎儿血红蛋白吸收特性。
J Clin Monit. 1988 Jul;4(3):175-7. doi: 10.1007/BF01621812.

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