Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Am J Respir Crit Care Med. 2013 May 15;187(10):1098-103. doi: 10.1164/rccm.201211-1969OC.
The heat-related risk of hospitalization for respiratory diseases among the elderly has not been quantified in the United States on a national scale. With climate change predictions of more frequent and more intense heat waves, it is of paramount importance to quantify the health risks related to heat, especially for the most vulnerable.
To estimate the risk of hospitalization for respiratory diseases associated with outdoor heat in the U.S. elderly.
An observational study of approximately 12.5 million Medicare beneficiaries in 213 United States counties, January 1, 1999 to December 31, 2008. We estimate a national average relative risk of hospitalization for each 10°F (5.6°C) increase in daily outdoor temperature using Bayesian hierarchical models.
We obtained daily county-level rates of Medicare emergency respiratory hospitalizations (International Classification of Diseases, Ninth Revision, 464-466, 480-487, 490-492) in 213 U.S. counties from 1999 through 2008. Overall, each 10°F increase in daily temperature was associated with a 4.3% increase in same-day emergency hospitalizations for respiratory diseases (95% posterior interval, 3.8, 4.8%). Counties' relative risks were significantly higher in counties with cooler average summer temperatures.
We found strong evidence of an association between outdoor heat and respiratory hospitalizations in the largest population of elderly studied to date. Given projections of increasing temperatures from climate change and the increasing global prevalence of chronic pulmonary disease, the relationship between heat and respiratory morbidity is a growing concern.
在美国,尚未对老年人因高温导致的呼吸系统疾病住院风险进行全国范围内的量化研究。随着气候变化预测热浪出现的频率和强度会增加,量化与高温相关的健康风险至关重要,尤其是对最脆弱的人群而言。
评估美国老年人因户外高温导致的呼吸系统疾病住院风险。
本研究采用观察性方法,共纳入 1999 年 1 月 1 日至 2008 年 12 月 31 日期间全美 213 个县约 1250 万医疗保险受益人的数据。采用贝叶斯层次模型,我们估计了每日户外温度每升高 10°F(5.6°C)时,与住院相关的全国平均相对风险。
本研究获取了全美 213 个县 1999 年至 2008 年期间每日县一级的医疗保险急诊呼吸系统疾病住院率(国际疾病分类,第 9 版,464-466、480-487、490-492)。总体而言,每日温度升高 10°F 与当天呼吸系统疾病急诊住院率增加 4.3%相关(95%后验区间,3.8,4.8%)。在夏季平均气温较低的县,相对风险更高。
我们发现,户外高温与呼吸系统疾病住院之间存在显著关联,这在迄今为止研究的最大老年人群中得到了有力证据支持。鉴于气候变化导致的气温升高预测以及慢性肺部疾病在全球的患病率不断增加,高温与呼吸系统发病率之间的关系日益受到关注。