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致命性莱姆病性心肌炎与房室结内胚层异位

Fatal Lyme carditis and endodermal heterotopia of the atrioventricular node.

作者信息

Cary N R, Fox B, Wright D J, Cutler S J, Shapiro L M, Grace A A

机构信息

Department of Histopathology, Charing Cross and Westminster School, London, UK.

出版信息

Postgrad Med J. 1990 Feb;66(772):134-6. doi: 10.1136/pgmj.66.772.134.

DOI:10.1136/pgmj.66.772.134
PMID:2349186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2429516/
Abstract

A fatal case of Lyme carditis occurring in a Suffolk farmworker is reported. Post-mortem examination of the heart showed pericarditis, focal myocarditis and prominent endocardial and interstitial fibrosis. The additional finding of endodermal heterotopia ('mesothelioma') of the atrioventricular node raises the possibility that this could also be related to Lyme infection and account for the relatively frequent occurrence of atrioventricular block in this condition. Lyme disease should always be considered in a case of atrioventricular block, particularly in a young patient from a rural area. The heart block tends to improve and therefore only temporary pacing may be required.

摘要

报告了一例发生在萨福克郡农场工人身上的莱姆病性心肌炎致死病例。心脏尸检显示心包炎、局灶性心肌炎以及显著的心内膜和间质纤维化。房室结内胚层异位(“间皮瘤”)这一额外发现增加了其也可能与莱姆感染有关的可能性,并解释了在这种情况下房室传导阻滞相对频繁发生的原因。对于房室传导阻滞病例,尤其是来自农村地区的年轻患者,应始终考虑莱姆病。心脏传导阻滞往往会改善,因此可能仅需要临时起搏。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcd4/2429516/909e808f051c/postmedj00158-0062-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcd4/2429516/e49c77fa85ad/postmedj00158-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcd4/2429516/9324872975e8/postmedj00158-0062-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcd4/2429516/909e808f051c/postmedj00158-0062-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcd4/2429516/e49c77fa85ad/postmedj00158-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcd4/2429516/9324872975e8/postmedj00158-0062-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcd4/2429516/909e808f051c/postmedj00158-0062-c.jpg

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本文引用的文献

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Lyme carditis: cardiac abnormalities of Lyme disease.莱姆病性心脏炎:莱姆病的心脏异常表现。
Ann Intern Med. 1980 Jul;93(1):8-16. doi: 10.7326/0003-4819-93-1-8.
2
Congenital polycystic tumor of the atrioventricular node (endodermal heterotopia, mesothelioma): a histogenetic appraisal with evidence for its endodermal origin.先天性房室结多囊性肿瘤(内胚层异位、间皮瘤):关于其起源于内胚层的组织发生学评估及证据
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[Cardiac involvement in Lyme disease. 2 cases].[莱姆病的心脏受累。2例]
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and Can Form Mixed Biofilms in Infected Human Skin Tissues.并且能够在受感染的人类皮肤组织中形成混合生物膜。
Eur J Microbiol Immunol (Bp). 2019 Apr 11;9(2):46-55. doi: 10.1556/1886.2019.00003. eCollection 2019 Jun 3.
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First case report of inducible heart block in Lyme disease and an update of Lyme carditis.首例莱姆病诱导性心脏传导阻滞病例报告及莱姆性心肌炎更新
BMC Infect Dis. 2019 May 16;19(1):428. doi: 10.1186/s12879-019-4025-0.
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Successful treatment of fulminant Lyme myocarditis with mechanical circulatory support in a young male adult: a case report.一名年轻男性成人暴发性莱姆心肌炎经机械循环支持成功治疗:病例报告
Croat Med J. 2017 Apr 14;58(2):185-193. doi: 10.3325/cmj.2017.58.185.
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Dtsch Arztebl Int. 2015 Mar 20;112(12):202-8. doi: 10.3238/arztebl.2015.0202.
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Three sudden cardiac deaths associated with Lyme carditis - United States, November 2012-July 2013.三例与莱姆心炎相关的心脏性猝死 - 美国,2012 年 11 月至 2013 年 7 月。
MMWR Morb Mortal Wkly Rep. 2013 Dec 13;62(49):993-6.
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