Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.
Am J Prev Med. 2013 Apr;44(4 Suppl 4):S339-45. doi: 10.1016/j.amepre.2012.12.014.
The gap between what is known from clinical efficacy research and the systematic community translation of diabetes prevention programs is narrowing. During the past 5 years, numerous randomized and nonrandomized dissemination studies have evaluated the modified delivery of structured Diabetes Prevention Program (DPP) interventions in diverse real-world settings. Programs of sufficient dose and duration, implemented with fidelity, have reported weight losses in the range of 4%-7% with associated improvements in cardiometabolic risk factors at 6 and 12 months from baseline. The current article describes some of the experiences and perspectives of a team of University of Pittsburgh researchers as they have engaged in these efforts.
临床疗效研究与糖尿病预防计划系统社区转化之间的差距正在缩小。在过去的 5 年中，许多随机和非随机的传播研究评估了在不同真实环境下对经过改良的结构化糖尿病预防计划（DPP）干预措施的实施。在足够剂量和持续时间的情况下，实施忠实于计划的方案，已经报告了体重减轻范围在 4%-7%，并且在 6 个月和 12 个月时与心血管代谢危险因素相关的改善。本文介绍了匹兹堡大学研究团队在参与这些努力时的一些经验和观点。
