Haider Shahzad, Wright David
Department of Paediatrics, Macclesfield District General Hospital, Macclesfield, UK.
BMJ Case Rep. 2013 Mar 14;2013:bcr2012007655. doi: 10.1136/bcr-2012-007655.
Panton-Valentine leukocidin (PVL) toxin producing strains of Staphylococcus aureus are known to cause skin and soft tissue infection. They can also cause necrotising pneumonia in otherwise healthy individuals. Here we report a case of severe, necrotising, haemorrhagic pneumonia in a 12-year-old boy who presented with a four-day history of a sore throat and fever. During his admission he deteriorated and needed full ventilatory support but despite all efforts he died. Postmortem examination lung swabs confirmed the presence of PVL-associated S aureus. There is a need to improve awareness of this disease among medical practitioners as early diagnosis and appropriate management can save lives.
已知产杀白细胞素(PVL)的金黄色葡萄球菌菌株可引起皮肤和软组织感染。它们也可在原本健康的个体中导致坏死性肺炎。在此,我们报告一例12岁男孩患严重、坏死性、出血性肺炎的病例,该男孩有四天的咽痛和发热病史。住院期间病情恶化,需要完全通气支持,但尽管全力救治仍死亡。尸检肺拭子证实存在与PVL相关的金黄色葡萄球菌。有必要提高医生对这种疾病的认识,因为早期诊断和适当治疗可挽救生命。