Dept. of Neurology, Washington University School of Medicine, St. Louis, MO, United States.
Brain Lang. 2013 May;125(2):231-43. doi: 10.1016/j.bandl.2012.12.016. Epub 2013 Mar 16.
Reading requires coordinated neural processing across a large number of brain regions. Studying relationships between reading-related regions informs the specificity of information processing performed in each region. Here, regions of interest were defined from a meta-analysis of reading studies, including a developmental study. Relationships between regions were defined as temporal correlations in spontaneous fMRI signal; i.e., resting state functional connectivity MRI (RSFC). Graph theory based network analysis defined the community structure of the "reading-related" regions. Regions sorted into previously defined communities, such as the fronto-parietal and cingulo-opercular control networks, and the default mode network. This structure was similar in children, and no apparent "reading" community was defined in any age group. These results argue against regions, or sets of regions, being specific or preferential for reading, instead indicating that regions used in reading are also used in a number of other tasks.
阅读需要大脑中大量区域的协调神经处理。研究与阅读相关区域之间的关系，可以揭示每个区域执行的信息处理的特异性。在这里，从阅读研究的元分析中定义了感兴趣的区域，包括一项发展研究。区域之间的关系被定义为自发 fMRI 信号的时间相关性，即静息态功能连接磁共振成像（RSFC）。基于图论的网络分析定义了“阅读相关”区域的社区结构。区域按照先前定义的社区进行排序，例如额顶叶和扣带回额回控制网络以及默认模式网络。这种结构在儿童中是相似的，并且在任何年龄组中都没有定义明显的“阅读”社区。这些结果表明，没有特定的区域或区域集是专门用于阅读的，而是表明用于阅读的区域也用于许多其他任务。
