Department of Family Medicine and Community Health, University of Minnesota, 717 Delaware Street S.E., Minneapolis, MN 55414, USA.
Addiction. 2013 Jun;108(6):1136-44. doi: 10.1111/add.12140. Epub 2013 Mar 19.
To assess the effects of adding motivational interviewing (MI) counseling to nicotine patch for smoking cessation among homeless smokers.
Two-group randomized controlled trial with 26-week follow-up.
A total of 430 homeless smokers from emergency shelters and transitional housing units in Minneapolis/St Paul, Minnesota, USA.
All participants received 8-week treatment of 21-mg nicotine patch. In addition, participants in the intervention group received six individual sessions of MI counseling which aimed to increase adherence to nicotine patches and to motivate cessation. Participants in the standard care control group received one session of brief advice to quit smoking. Primary outcome was 7-day abstinence from cigarette smoking at 26 weeks, as validated by exhaled carbon monoxide and salivary cotinine.
Using intention-to-treat analysis, verified 7-day abstinence rate at week 26 for the intervention group was non-significantly higher than for the control group (9.3% versus 5.6%, P = 0.15). Among participants who did not quit smoking, reduction in number of cigarettes from baseline to week 26 was equally high in both study groups (-13.7 ± 11.9 for MI versus -13.5 ± 16.2 for standard care).
Adding motivational interviewing counseling to nicotine patch did not increase smoking rate significantly at 26-week follow-up for homeless smokers.
评估在为无家可归的吸烟者提供尼古丁贴片戒烟治疗的基础上，增加动机访谈（MI）咨询对戒烟的影响。
一项为期 26 周随访的两臂随机对照试验。
共 430 名来自美国明尼苏达州明尼阿波利斯/圣保罗的紧急避难所和过渡性住房单元的无家可归吸烟者。
所有参与者均接受为期 8 周的 21mg 尼古丁贴片治疗。此外，干预组的参与者还接受了六次个体 MI 咨询，旨在提高对尼古丁贴片的依从性并激发戒烟动机。标准护理对照组的参与者接受了一次简短的戒烟建议。主要结局是在 26 周时通过呼出一氧化碳和唾液可替宁验证的 7 天戒烟率。
采用意向治疗分析，在 26 周时，干预组的 7 天戒烟率无显著高于对照组（9.3%比 5.6%，P=0.15）。在未戒烟的参与者中，两组研究参与者的基线至 26 周的吸烟量减少同样显著（MI 组减少 13.7±11.9 支，标准护理组减少 13.5±16.2 支）。
对于无家可归的吸烟者，在尼古丁贴片戒烟治疗的基础上增加动机访谈咨询，在 26 周随访时对戒烟率无显著影响。
