School of Ocean Sciences, China University of Geosciences, Beijing 100083, China.
Mar Drugs. 2013 Mar 13;11(3):842-7. doi: 10.3390/md11030842.
Chemical investigation of a Chinese collection of marine red alga Symphyocladia latiuscula yielded two new highly brominated phenols. The structures of the new compounds were elucidated by detailed spectroscopic analysis, including HRMS, 1D and 2D NMR and MS methods. Compounds 1 and 2 were evaluated for radical scavenging capability by 1,1-diphenyl-2-picrylhydrazuyl (DPPH) radical with the IC50 value of 14.5 and 20.5 μg/mL, respectively.
从中国采集的海洋红藻 S. latiuscula 中进行了化学研究，得到了两个新的高度溴化酚类化合物。通过详细的光谱分析，包括高分辨质谱、1D 和 2D NMR 和 MS 方法，确定了新化合物的结构。通过 1,1-二苯基-2-苦基肼（DPPH）自由基清除能力评估了化合物 1 和 2 的自由基清除能力，IC50 值分别为 14.5 和 20.5μg/mL。
