Yi Ling-Xiao, Fang Rou, Chen Guan-Hua
College of Food and Bioengineering, Jiangsu University, Zhenjiang 212013, China.
J Chromatogr Sci. 2013 Aug;51(7):608-18. doi: 10.1093/chromsci/bmt024. Epub 2013 Mar 28.
The molecular imprinting technique is a highly predeterminative recognition technology. Molecularly imprinted polymers (MIPs) can be applied to the cleanup and preconcentration of analytes as the selective adsorbent of solid-phase extraction (SPE). In recent years, a new type of SPE has formed, molecularly imprinted polymer solid-phase extraction (MISPE), and has been widely applied to the extraction of agrochemicals. In this review, the mechanism of the molecular imprinting technique and the methodology of MIP preparations are explained. The extraction modes of MISPE, including offline and online, are discussed, and the applications of MISPE in the analysis of agrochemicals such as herbicides, fungicides and insecticides are summarized. It is concluded that MISPE is a powerful tool to selectively isolate agrochemicals from real samples with higher extraction and cleanup efficiency than commercial SPE and that it has great potential for broad applications.
分子印迹技术是一种具有高度预定性的识别技术。分子印迹聚合物（MIPs）作为固相萃取（SPE）的选择性吸附剂，可应用于分析物的净化和预富集。近年来，一种新型的SPE——分子印迹聚合物固相萃取（MISPE）已形成，并已广泛应用于农用化学品的萃取。在这篇综述中，解释了分子印迹技术的机理和MIP制备方法。讨论了MISPE的萃取模式，包括离线和在线模式，并总结了MISPE在除草剂、杀菌剂和杀虫剂等农用化学品分析中的应用。得出的结论是，MISPE是一种从实际样品中选择性分离农用化学品的有力工具，其萃取和净化效率高于商业SPE，具有广阔的应用潜力。
