University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK.
Clin Transl Allergy. 2013 Apr 1;3(1):13. doi: 10.1186/2045-7022-3-13.
The European Academy of Allergy and Clinical Immunology is in the process of developing its Guideline for Food Allergy and Anaphylaxis, and this protocol of a systematic review is one of seven inter-linked evidence syntheses that are being undertaken in order to provide a state-of-the-art synopsis of the current evidence base in relation to epidemiology, prevention, diagnosis and clinical management and impact on quality of life, which will be used to inform the formulation of clinical recommendations.The aims of the systematic review will be to understand and describe the epidemiology of food allergy, i.e. frequency, risk factors and outcomes of patients suffering from food allergy, and to describe how these characteristics vary by person, place and time.
A highly sensitive search strategy has been developed to retrieve articles that have investigated the various aspects of the epidemiology of food allergy. The search will be implemented by combining the concepts of food allergy and its epidemiology from electronic bibliographic databases.
This systematic review will provide the most up to date estimates of the frequency of food allergy in Europe. We will attempt to break these down by age and geographical region in Europe. Our analysis will take into account the suitability of the study design and the respective study biases that could affect exposure and outcome. We will examine the different methods to diagnose food allergy and the associated measures of occurrence.
欧洲过敏与临床免疫学会正在制定食物过敏和过敏反应指南，本系统评价方案是正在进行的七个相互关联的证据综合之一，旨在提供有关食物过敏的当前证据基础的最新概述，包括流行病学、预防、诊断和临床管理以及对生活质量的影响，这些将用于为临床建议的制定提供信息。系统评价的目的是了解和描述食物过敏的流行病学，即患有食物过敏的患者的频率、风险因素和结果，并描述这些特征如何因人和时间而异。
制定了一种高度敏感的搜索策略，以检索调查食物过敏各个方面的文章。将通过结合食物过敏及其流行病学的概念从电子书目数据库中进行搜索。
本系统评价将提供欧洲食物过敏频率的最新估计。我们将尝试根据年龄和欧洲地理区域对其进行细分。我们的分析将考虑到研究设计的适宜性和可能影响暴露和结果的各自研究偏倚。我们将检查诊断食物过敏的不同方法以及相关的发生率测量方法。
