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[木槿(玫瑰茄)的体外酶抑制和体内心脏保护活性]

[In vitro enzyme inhibitory and in vivo cardioprotective activities of hibiscus (Hibiscus sabdariffa L.)].

作者信息

Jonadet M, Bastide J, Bastide P, Boyer B, Carnat A P, Lamaison J L

机构信息

C.N.R.S. U.F.R. de Pharmacie, Clermont-Ferrand.

出版信息

J Pharm Belg. 1990 Mar-Apr;45(2):120-4.

PMID:2355305
Abstract

A crude hydroalcoholic extract from Hibiscus sabdariffa L. calyces showed in vitro an appreciable enzyme-inhibiting activity towards the Angiotensin I Converting Enzyme (ACE), attributable to flavones, but weak inhibiting activities towards elastase, trypsin and alpha-chymotrypsin. The angioprotective activity in vivo, also important, was due to flavones and anthocyanins.

摘要

来自玫瑰茄萼片的粗制水醇提取物在体外对血管紧张素I转换酶(ACE)显示出明显的酶抑制活性,这归因于黄酮类化合物,但对弹性蛋白酶、胰蛋白酶和α-胰凝乳蛋白酶的抑制活性较弱。体内血管保护活性也很重要,这归因于黄酮类化合物和花青素。

相似文献

1
[In vitro enzyme inhibitory and in vivo cardioprotective activities of hibiscus (Hibiscus sabdariffa L.)].[木槿(玫瑰茄)的体外酶抑制和体内心脏保护活性]
J Pharm Belg. 1990 Mar-Apr;45(2):120-4.
2
Phytochemical, pharmacological and toxicological aspects of Hibiscus sabdariffa L.: a review.玫瑰茄的植物化学、药理学和毒理学方面:综述
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[Flavonoids extracted from Ribes nigrum L. and Alchemilla vulgaris L.: 1. In vitro inhibitory activities on elastase, trypsin and chymotrypsin. 2. Angioprotective activities compared in vivo].[从黑醋栗和普通羽衣草中提取的类黄酮:1. 对弹性蛋白酶、胰蛋白酶和糜蛋白酶的体外抑制活性。2. 体内血管保护活性比较]
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Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa.矢车菊素-3-O-新橙皮糖苷和飞燕草素-3-O-新橙皮糖苷对藏红花酸二氢查尔酮的抑制作用。
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Effect of Hibiscus anthocyanins-rich extract induces apoptosis of proliferating smooth muscle cell via activation of P38 MAPK and p53 pathway.富含木槿花青素的提取物通过激活P38丝裂原活化蛋白激酶和p53途径诱导增殖平滑肌细胞凋亡。
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Effect of Hibiscus sabdariffa and its anthocyanins on some reproductive aspects in rats.玫瑰茄及其花青素对大鼠某些生殖方面的影响。
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[In vitro and in vivo studies on the cardioprotective action of oligomeric procyanidins in a Crataegus extract of leaves and blooms].[原花青素低聚物在山楂叶花提取物中对心脏保护作用的体外和体内研究]
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Dose-dependent changes in some haematological parameters during short-term administration of Hibiscus sabdariffa Calyx aqueous extract (Zobo) in Wistar albino rats.在Wistar白化大鼠短期给予玫瑰茄花萼水提取物(佐博)期间某些血液学参数的剂量依赖性变化。
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J Ethnopharmacol. 2007 Oct 8;114(1):66-71. doi: 10.1016/j.jep.2007.07.020. Epub 2007 Jul 27.

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Antihypertensive Effects of Roselle-Olive Combination in L-NAME-Induced Hypertensive Rats.洛神花-油橄榄组合对 L-NAME 诱导的高血压大鼠的降压作用。
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Identification and Characterization of Roseltide, a Knottin-type Neutrophil Elastase Inhibitor Derived from Hibiscus sabdariffa.
从黄蜀葵中鉴定和表征 Roseltide,一种 knotin 型中性粒细胞弹性蛋白酶抑制剂。
Sci Rep. 2016 Dec 19;6:39401. doi: 10.1038/srep39401.
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Does consumption of an aqueous extract of Hibscus sabdariffa affect renal function in subjects with mild to moderate hypertension?食用玫瑰茄水提取物会影响轻至中度高血压患者的肾功能吗?
J Physiol Sci. 2017 Jan;67(1):227-234. doi: 10.1007/s12576-016-0458-z. Epub 2016 May 24.
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Determination of antimicrobial activity of sorrel (Hibiscus sabdariffa) on Escherichia coli O157:H7 isolated from food, veterinary, and clinical samples.测定食物、兽医和临床样本中分离的大肠杆菌 O157:H7 对洛神花( Hibiscus sabdariffa )的抗菌活性。
J Med Food. 2011 Sep;14(9):950-6. doi: 10.1089/jmf.2010.0200. Epub 2011 May 6.
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