Campus de la Universidad Autónoma de Madrid, Madrid, Spain.
Patient. 2013;6(2):61-73. doi: 10.1007/s40271-013-0009-0.
Since the use of the questionnaire to evaluate adherence to HIV therapy (acronym CEAT-VIH) has increased in the last decade and translation into new language versions has been requested, summarizing information regarding the psychometric properties of the instrument may be useful for researchers and practitioners.
The purpose of this work was to review the psychometric properties of the questionnaire CEAT-VIH, available from published studies and research reports.
Medline, PsycINFO, Google Scholar and Google; the searched period was from 2001 to 2012.
Forty-eight research materials referring to the questionnaire CEAT-VIH were initially gathered from academic databases and direct contact with researchers, before being analyzed. From the initial pool of material compiled (i.e., abstracts, technical reports or database files, dissertations or complete articles), only 20 comprised original data.
The selected research material described a variety of information in terms of the psychometric properties of the questionnaire. The results from the primary studies were then summarized in tables for evaluation, description and comparison.
Thirteen out of 16 studies reported a Cronbach's alpha value of above 0.70, supporting the internal consistency reliability of the CEAT-VIH questionnaire. No floor or ceiling effects were observed. Hypothesized relationships between the CEAT-VIH score and adherence-related variables (e.g., viral load, CD4+, compliance evaluated by physician or pharmacist, complexity of treatment and pill numbers) were observed, indicating validity evidence. Thus, variables expected to act as psychological risk factors for low adherence (e.g., stress, depression and anxiety) or protector factor (e.g., social support) to good adherence were observed. The scores of the questionnaire were also related to quality of life outcomes. Moreover, patients that received adherence intervention showed increased CEAT-VIH adherence scores. Sensitivity and specificity to correctly identify adherent patients with undetectable viral load were also observed for three studies.
Although the data provided in the reports were heterogeneous, these were valuable and reported enough evidence of validity for the instrument. The selected studies represented 41.7 % of those initially identified, and only eight out of 20 documents were peer reviewed.
The CEAT-VIH has been used for a variety of individuals of different ages, sex, socioeconomic and educational backgrounds. It has been a reliable and valid tool in measuring adherence to HIV treatment among different samples, and has been used with a wide range of study populations and countries (i.e., Brazil, Chile, Colombia, Mexico, Panama, Peru, Portugal, Puerto Rico, Romania and Spain). Encouraging data reported here may allow the recommendation of the CEAT-VIH as a valuable measure to use in HIV adherence research, especially in countries where the questionnaire already has available psychometric evidence.
自十年来，问卷被广泛用于评估 HIV 治疗的依从性（CEAT-VIH 缩写），且新的语言版本的翻译也已被要求，因此总结该工具的心理测量学特性的信息可能对研究人员和从业者有用。
本研究旨在综述问卷 CEAT-VIH 的心理测量学特性，该问卷可从已发表的研究和研究报告中获得。
Medline、PsycINFO、Google Scholar 和 Google；检索时间为 2001 年至 2012 年。
从学术数据库和与研究人员的直接联系中，最初共收集了 48 份关于问卷 CEAT-VIH 的研究资料，然后进行分析。从最初编译的资料（即摘要、技术报告或数据库文件、论文或完整文章）中，只有 20 份包含原始数据。
所选研究资料从心理测量学的角度描述了问卷的各种信息。然后，将主要研究的结果总结在表格中进行评估、描述和比较。
16 项研究中有 13 项报告了 Cronbach's alpha 值大于 0.70，支持 CEAT-VIH 问卷的内部一致性信度。未观察到地板效应或天花板效应。观察到 CEAT-VIH 评分与依从性相关变量（例如病毒载量、CD4+、医生或药剂师评估的依从性、治疗复杂性和药丸数量）之间的假设关系，表明该问卷具有有效性证据。因此，观察到了预期作为低依从性的心理风险因素（例如压力、抑郁和焦虑）或保护因素（例如社会支持）的变量。问卷的分数也与生活质量结果有关。此外，接受依从性干预的患者显示出 CEAT-VIH 依从性评分增加。还观察到三项研究中，正确识别病毒载量不可检测的依从性患者的敏感性和特异性。
尽管报告中的数据具有异质性，但这些数据很有价值，并为该工具提供了足够的有效性证据。所选研究仅代表最初确定的研究的 41.7%，且 20 份文件中只有 8 份经过同行评审。
CEAT-VIH 已被用于不同年龄、性别、社会经济和教育背景的各种人群。它是一种可靠和有效的工具，可用于测量不同样本中 HIV 治疗的依从性，并已在广泛的研究人群和国家（即巴西、智利、哥伦比亚、墨西哥、巴拿马、秘鲁、葡萄牙、波多黎各、罗马尼亚和西班牙）中使用。这里报告的令人鼓舞的数据可能允许推荐 CEAT-VIH 作为 HIV 依从性研究中有用的测量工具，特别是在问卷已经具有心理测量学证据的国家。
