Liver Research Unit, Medica Sur Clinic & Foundation. Mexico City, Mexico.
Ann Hepatol. 2013 Mar-Apr;12 Suppl 2:s3-35.
Hepatitis C is a common cause of end-stage liver disease, and the main indication for liver transplantation in Latin America. Treatment of hepatitis C infected patients improves important long-term outcomes as mortality. Sustained viral response is reached in near 50% of patients with the previous management based in pegylated interferon and ribavirin. Recently new drugs were available increasing sustained viral response significantly, changing the standard of care to triple therapy. This guidelines provides a framework for practitioner in Latin America, to the management of patients with hepatitis C chronic infection.
丙型肝炎是终末期肝病的常见病因,也是拉丁美洲进行肝移植的主要指征。治疗丙型肝炎感染患者可改善重要的长期预后,如死亡率。在以前基于聚乙二醇干扰素和利巴韦林的治疗中,近 50%的患者达到了持续病毒学应答。最近,新的药物问世,显著提高了持续病毒学应答率,改变了三联疗法的治疗标准。本指南为拉丁美洲的临床医生提供了一个框架,用于管理慢性丙型肝炎感染患者。