Glostrup University Hospital, Glostrup, Denmark
Glostrup University Hospital, Glostrup, Denmark.
Eur J Prev Cardiol. 2014 Oct;21(10):1300-7. doi: 10.1177/2047487313485517. Epub 2013 Apr 4.
A simple and valid alternative for 24-hour urine collection to estimate populational 24-hour urinary sodium excretion would be desirable for monitoring sodium intake in populations.
To assess the validity of the predicted 24-hour urinary sodium excretion using spot urine and two different prediction methods in a Danish population.
Overall, 473 Danish individuals provided a para-aminobenzoic acid-validated complete 24-hour urine collection and a spot urine sample. Data were collected in the DanThyr study (248 women aged 25-30 years and 60-65 years) and the Inter99 study (102 men and 113 women aged 30-60 years), respectively. The measured 24-hour urine sodium excretion was compared with the predicted 24-hour sodium excretion from a causal urine specimen, using both the Tanaka prediction method and a prediction model developed in a Danish population.
The measured 24-hour sodium excretion (median, 5th to 95th percentile) was men 195 (110 to 360) and women 139 (61 to 258), whereas the predicted 24-hour sodium excretion for the Tanaka model was men 171 (117 to 222) and women 153 (92 to 228) and for the Danish model was men 207 (146 to 258); women 134 (103 to 163). The Spearman correlation between predicted and measured 24-hour sodium excretion was 0.39 and 0.49 for the Tanaka and the Danish model, respectively. For both prediction models, the proportion of individuals classified in the same or adjacent quintile was 74% for men and 64% for women.
Both prediction models gave a reasonable classification of individuals according to their sodium excretion. However, the median daily sodium intake was estimated more precisely by the Danish model, especially among men.
对于监测人群的钠摄入量，人们希望有一种简单有效的替代 24 小时尿液收集的方法来估计人群的 24 小时尿钠排泄量。
评估丹麦人群中使用单次尿样和两种不同预测方法预测 24 小时尿钠排泄量的准确性。
共有 473 名丹麦人提供了一份经对氨基苯甲酸验证的完整 24 小时尿液收集和一份单次尿液样本。数据分别来自丹泰尔研究（248 名年龄在 25-30 岁和 60-65 岁的女性）和国际 99 研究（102 名男性和 113 名年龄在 30-60 岁的女性）。使用因果尿液样本的 Tanaka 预测方法和丹麦人群中开发的预测模型，将测量的 24 小时尿钠排泄量与预测的 24 小时尿钠排泄量进行比较。
测量的 24 小时钠排泄量（中位数，第 5 至 95 百分位数）为男性 195（110-360）和女性 139（61-258），而 Tanaka 模型预测的 24 小时钠排泄量为男性 171（117-222）和女性 153（92-228），丹麦模型预测的 24 小时钠排泄量为男性 207（146-258）；女性 134（103-163）。Tanaka 模型和丹麦模型预测的 24 小时钠排泄量之间的 Spearman 相关系数分别为 0.39 和 0.49。对于两种预测模型，男性和女性的个体分类在相同或相邻五分位数的比例分别为 74%和 64%。
两种预测模型都能根据个体的钠排泄量对个体进行合理分类。然而，丹麦模型尤其在男性中，对每日钠摄入量的估计更为准确。
