Department of Anesthesiology and Pain Medicine, School of Medicine, Catholic University of Daegu, Daegu, Korea.
Korean J Anesthesiol. 2013 Mar;64(3):246-50. doi: 10.4097/kjae.2013.64.3.246. Epub 2013 Mar 19.
In general, measuring the level of consciousness in neurological patients is important. To assess the patient's mental status, the Glasgow Coma Scale (GCS) and the level of consciousness (drowsiness, stupor, and coma) have been used in clinical situations. The aim of the present study was to identify the correlation between bispectral index (BIS) and level of consciousness in brain injured patients.
Eighty-nine adult patients of both sexes were included in the study. A blinded observer evaluated the mental status (GCS and level of consciousness) of a patient who is admitted in intensive care unit with brain injury, while an investigator noted the patient's BIS. The BIS was measured using a BIS monitor, Model A-3000 vista™ with Sensor Bis quatro™ (Aspect Medical Systems, Norwood, USA). A Spearman's rank correlation coefficient was used to determine if the level of consciousness correlated with the BIS.
In 89 patients, the BIS was found to be significantly correlated with the level of consciousness (r = 0.723, P < 0.01) and GCS (r = 0.646, P < 0.01). The BIS values increased with an increasing level of consciousness. Mean BIS values of coma, semicoma, stupor and drowsiness were 0.14 ± 0.23, 38.9 ± 18.0, 60.3 ± 14.5, and 73.6 ± 16.5, respectively.
In the present study, a significant correlation existed between level of consciousness and BIS. These findings suggest that BIS may be used for assessing the level of consciousness in brain injured patients. However, the scatter of BIS values for any level of consciousness limited the worth of BIS in predicting mentality except in coma patients.
一般来说，测量神经患者的意识水平很重要。为了评估患者的精神状态，格拉斯哥昏迷量表（GCS）和意识水平（嗜睡、昏迷和昏迷）已在临床情况下使用。本研究的目的是确定脑损伤患者脑电双频指数（BIS）与意识水平之间的相关性。
本研究纳入了 89 名成年男女患者。一名盲法观察者评估了入住重症监护病房的脑损伤患者的精神状态（GCS 和意识水平），而一名研究者则记录了患者的 BIS。BIS 使用 BIS 监测仪 Model A-3000 vista™ with Sensor Bis quatro™（Aspect Medical Systems，Norwood，USA）进行测量。采用 Spearman 秩相关系数来确定意识水平与 BIS 是否相关。
在 89 名患者中，BIS 与意识水平（r = 0.723，P < 0.01）和 GCS（r = 0.646，P < 0.01）呈显著相关。BIS 值随意识水平的增加而增加。昏迷、半昏迷、昏迷和嗜睡的平均 BIS 值分别为 0.14 ± 0.23、38.9 ± 18.0、60.3 ± 14.5 和 73.6 ± 16.5。
在本研究中，意识水平与 BIS 之间存在显著相关性。这些发现表明，BIS 可用于评估脑损伤患者的意识水平。然而，除昏迷患者外，BIS 对任何意识水平的预测价值都受到 BIS 值的分散限制。
