Mujawar Anjum H, Bhalerao Pradnya M, Kshirsagar Sujit J
Department of Anaesthesiology, B. J. Medical College, Pune, India.
Department of Anaesthesiology, Government Medical College and General Hospital, Baramati, Baramati, India.
J Trauma Inj. 2025 Jun;38(2):97-102. doi: 10.20408/jti.2025.0026. Epub 2025 Jun 30.
Traumatic brain injury (TBI) severity is typically assessed using the Glasgow Coma Scale (GCS). In contrast, the bispectral index (BIS) objectively evaluates a patient's level of consciousness in an intensive care unit. The primary objective of this study was to evaluate the correlation between GCS and BIS values in TBI patients. Secondary objectives included determining the range of BIS scores corresponding to different levels of consciousness and assessing the correlation among mild, moderate, and severe TBI.
Sixty patients participated in a prospective observational study conducted at a government tertiary care facility. After obtaining a detailed history and performing a physical examination, each patient's age, sex, intubation status, computed tomography brain findings, and vital signs were recorded. Subsequently, the patients' GCS and BIS values were measured at 0, 6, 12, 18, and 24 hours. Quantitative data are presented as mean±standard deviation, while qualitative data are illustrated using frequency and percentage tables. Spearman correlation analysis was employed to evaluate the association.
Spearman correlation analysis demonstrated a strong positive relationship between BIS and GCS at 0 hours (r=0.655, P<0.05), 6 hours (r=0.647, P<0.05), 12 hours (r=0.652, P<0.05), 18 hours (r=0.659, P<0.05), and 24 hours (r=0.648, P<0.05). Moreover, the mean BIS value decreased significantly with increasing severity of head injury.
Similar to the GCS, the BIS correlates with head injury severity and may serve as a complementary tool for predicting outcomes in TBI patients.
创伤性脑损伤（TBI）的严重程度通常使用格拉斯哥昏迷量表（GCS）进行评估。相比之下，脑电双频指数（BIS）可客观评估重症监护病房患者的意识水平。本研究的主要目的是评估TBI患者GCS与BIS值之间的相关性。次要目的包括确定与不同意识水平相对应的BIS评分范围，以及评估轻度、中度和重度TBI之间的相关性。
60例患者参与了在一家政府三级护理机构进行的前瞻性观察性研究。在获取详细病史并进行体格检查后，记录每位患者的年龄、性别、插管状态、脑部计算机断层扫描结果和生命体征。随后，在0、6、12、18和24小时测量患者的GCS和BIS值。定量数据以平均值±标准差表示，而定性数据则使用频率和百分比表进行说明。采用Spearman相关性分析来评估这种关联。
Spearman相关性分析表明，在0小时（r = 0.655，P < 0.05）、6小时（r = 0.647，P < 0.05）、12小时（r = 0.652，P < 0.05）、18小时（r = 0.659，P < 0.05）和24小时（r = 0.648，P < 0.05）时，BIS与GCS之间存在强正相关。此外，随着头部损伤严重程度的增加，平均BIS值显著降低。
与GCS类似，BIS与头部损伤严重程度相关，可作为预测TBI患者预后的补充工具。
