Maier C, Schele H A, Haverlach T
Zentrale Abteilung für Anaesthesie, Christian-Albrechts-Universität, Kiel.
Reg Anaesth. 1990 May;13(3):88-90.
We report 4 cases of inadvertent subdural injection of local anesthetics among 640 patients receiving epidural anesthesia. In contrast to subarachnoid injection a typical sign was the development of patchy anesthesia in cervical segments and with late onset of symptoms. The case of a 63 year old woman scheduled for aortofemoral bypass surgery in epidural anesthesia is reported. She developed paresthesia, paresis and signs of sympatholysis in both arms 30 min after the injection of 10 ml bupivacaine 0.5% at T10-11. These symptoms lasted for 7 h. Subdural injection was documented using radiopaque dye. Two other cases of probable subdural injection leading to paresthesia and paresis in cervical segments after lumbar injection of 50 or 75 mg bupivacaine are reported. The symptoms began 15-30 min after injection and lasted for 60 min. The fourth case was that of a 26-year-old woman scheduled for cesarean section under epidural anesthesia. Following the injection of 75 mg bupivacaine 0.5% patchy anesthesia extending to T10 developed. By 10 min after an additional injection of 25 mg bupivacaine 0.5% she had paresis and paresthesia in both arms and was unable to cough. Her trachea was therefore intubated; 30 min later the level of anesthesia was below T5 and she could be extubated. Uneventful cesarean section was then performed. These cases demonstrate that as well as subarachnoid injection, inadvertent subdural injection of local anesthetic agents is a potential hazard of epidural anesthesia, not only in patients in an advanced state of pregnancy but also in nonpregnant patients.(ABSTRACT TRUNCATED AT 250 WORDS)
我们报告了640例接受硬膜外麻醉的患者中4例意外硬膜下注射局部麻醉剂的病例。与蛛网膜下腔注射不同,典型症状是颈部节段出现片状麻醉且症状出现较晚。报告了1例63岁女性计划在硬膜外麻醉下行主-股动脉搭桥手术的病例。在T10 - 11间隙注射10 ml 0.5%布比卡因30分钟后,她双臂出现感觉异常、轻瘫和交感神经阻滞症状。这些症状持续了7小时。使用不透X线染料证实了硬膜下注射。还报告了另外2例可能的硬膜下注射病例,在腰段注射50或75 mg布比卡因后导致颈部节段感觉异常和轻瘫。症状在注射后15 - 30分钟开始,持续60分钟。第4例是1例26岁女性计划在硬膜外麻醉下行剖宫产手术。注射75 mg 0.5%布比卡因后出现延伸至T10的片状麻醉。在额外注射25 mg 0.5%布比卡因10分钟后,她双臂出现轻瘫和感觉异常,无法咳嗽。因此对她进行了气管插管;30分钟后麻醉平面低于T5,她可以拔管。随后顺利进行了剖宫产手术。这些病例表明,除了蛛网膜下腔注射外,意外硬膜下注射局部麻醉剂是硬膜外麻醉的一个潜在风险,不仅在晚期妊娠患者中存在,在非妊娠患者中也存在。(摘要截短于250字)