Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Anticancer Res. 2013 Apr;33(4):1641-7.
To justify esophagectomy for elderly patients.
A total of 1,002 patients with thoracic esophageal cancer who underwent esophagectomy were divided into three groups: I (≤ 74 years old, n=898); II (75-79 years, n=81); and III (≥ 80 years, n=23). Historical changes were compared between the first surgical period (1964-1989) and the second period (1990-2011).
The morbidity rates were 40%, 41% and 26% in the respective groups. Pulmonary complications decreased historically in groups II and III (36% to 15% and 43% to 0%, respectively). The mortality was higher in the older groups (4.8%, 8.6% and 13.0%, respectively); however, there was a marked historical decrease in groups II (18.2% to 5.1%) and III (28.6% to 6.3%). The 5-year survival improved from 5% to 35% in group II and from 0% to 17% in group III.
The outcomes of esophagectomy for elderly patients have markedly improved, with acceptable mortality even in octogenarians.
证明老年患者行食管癌切除术的合理性。
共有 1002 例行食管癌切除术的胸段食管癌症患者被分为三组：I 组（≤74 岁，n=898）；II 组（75-79 岁，n=81）；III 组（≥80 岁，n=23）。比较了第一个手术期（1964-1989 年）和第二个手术期（1990-2011 年）之间的历史变化。
各组的发病率分别为 40%、41%和 26%。肺并发症在 II 组和 III 组中呈历史下降趋势（36%降至 15%，43%降至 0%）。年龄较大的组死亡率较高（4.8%、8.6%和 13.0%）；然而，II 组（18.2%降至 5.1%）和 III 组（28.6%降至 6.3%）的死亡率明显下降。II 组的 5 年生存率从 5%提高到 35%，III 组从 0%提高到 17%。
老年患者食管癌切除术的结果明显改善，即使是 80 岁以上的患者，死亡率也可接受。
