Nationwide Children's Hospital, Columbus, Ohio 43205, USA.
Respir Care. 2013 Apr;58(4):e42-6. doi: 10.4187/respcare.01759.
A combination of helium and oxygen (heliox) can facilitate gas exchange and limit peak inspiratory pressures through reduced resistance to gas flow and decreased turbulent flow. The combination of these gases has been used for a variety of upper and lower airway conditions, including patients who were spontaneously breathing, receiving noninvasive ventilation, as well as during mechanical ventilation. To date, there are no reports regarding the use of heliox in patients with bronchiolitis obliterans syndrome following lung transplantation. We report the use of such a combination of gases in 2 patients with bronchiolitis obliterans syndrome following lung transplantation as a supportive measure to facilitate ventilation during the initial treatment course for acute respiratory failure in the ICU. A heliox mixture was administered with noninvasive ventilation and with mechanical ventilation through the ventilator in a heart-lung transplant recipient and a lung transplant recipient, respectively.
氦气和氧气（氦氧混合气）的组合可以通过降低气流阻力和减少湍流来促进气体交换并限制吸气峰压。这种混合气体已被用于多种上呼吸道和下呼吸道疾病，包括自主呼吸、接受无创通气以及机械通气的患者。迄今为止，尚无关于在肺移植后闭塞性细支气管炎综合征患者中使用氦氧混合气的报道。我们报告了在 2 例肺移植后闭塞性细支气管炎综合征患者中使用这种混合气体，作为在 ICU 中急性呼吸衰竭初始治疗期间促进通气的支持措施。在心肺移植受者和肺移植受者中，分别通过无创通气和呼吸机给予氦氧混合气。
