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胰腺癌扩大淋巴结清扫至关重要。

Extended lymphadenectomy in pancreatic cancer is crucial.

机构信息

Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

出版信息

World J Surg. 2013 Aug;37(8):1778-81. doi: 10.1007/s00268-013-2039-0.

DOI:10.1007/s00268-013-2039-0
PMID:23568249
Abstract

Lymph node metastasis is considered one of the most significant factors associated with postoperative prognosis in patients with pancreatic cancer. Some prospective studies found no significant differences in survival between patients who underwent pancreatic cancer surgery with extended lymphadenectomy and those who underwent surgery with standard lymphadenectomy. However, recent reports, such as those describing the significance of the metastatic to examined lymph node ratio, suggest the need for some degree of lymphadenectomy. This review describes the findings of published studies and discusses the usefulness of LN dissection in patients with pancreatic cancer.

摘要

淋巴结转移被认为是与胰腺癌患者术后预后最相关的因素之一。一些前瞻性研究发现,行扩大淋巴结清扫术和标准淋巴结清扫术的胰腺癌患者的生存无显著差异。然而,最近的一些报告,如描述转移至检查淋巴结比率的意义的报告,提示需要进行一定程度的淋巴结清扫。本文综述了已发表研究的结果,并讨论了 LN 解剖术在胰腺癌患者中的应用价值。

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2
Extended lymphadenectomy in patients with pancreatic cancer is debatable.在胰腺癌患者中进行扩大淋巴结清扫术存在争议。
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本文引用的文献

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N0/N1, PNL, or LNR? The effect of lymph node number on accurate survival prediction in pancreatic ductal adenocarcinoma.N0/N1、PNL 还是 LNR?淋巴结数量对胰腺导管腺癌准确生存预测的影响。
J Gastrointest Surg. 2013 Feb;17(2):257-66. doi: 10.1007/s11605-012-1974-7. Epub 2012 Dec 11.
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Extended lymphadenectomy does not improve prognosis in pancreatic carcinoma: is that really so?
J Hepatobiliary Pancreat Sci. 2012 May;19(3):297-8; author reply 299. doi: 10.1007/s00534-011-0501-7.
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Cancer statistics, 2012.癌症统计数据,2012 年。
淋巴系统与胰腺癌
Cancer Lett. 2016 Oct 10;381(1):217-36. doi: 10.1016/j.canlet.2015.11.048. Epub 2015 Dec 29.
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Lymph node ratio is an independent prognostic factor for patients after resection of pancreatic cancer.淋巴结比率是胰腺癌切除术后患者的独立预后因素。
World J Surg Oncol. 2015 Mar 13;13:105. doi: 10.1186/s12957-015-0510-0.
5
Mesopancreas: A boundless structure, namely the rationale for dissection of the paraaortic area in pancreaticoduodenectomy for pancreatic head carcinoma.胰体中部:一种无边界的结构,即胰头癌胰十二指肠切除术中主动脉旁区域解剖的理论依据。
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Correlation between radiographic classification and pathological grade of portal vein wall invasion in pancreatic head cancer.胰腺癌门静脉壁侵犯的影像学分类与病理学分级的相关性。
Ann Surg. 2012 Jan;255(1):103-8. doi: 10.1097/SLA.0b013e318237872e.
5
Arterial resection during pancreatectomy for pancreatic cancer: a systematic review and meta-analysis.胰腺癌切除术时的动脉切除术:系统评价和荟萃分析。
Ann Surg. 2011 Dec;254(6):882-93. doi: 10.1097/SLA.0b013e31823ac299.
6
Standard versus extended lymphadenectomy in radical pancreatoduodenectomy for ductal adenocarcinoma of the head of the pancreas: long-term results of a Japanese multicenter randomized controlled trial.标准与扩大淋巴结清扫在胰头导管腺癌根治性胰十二指肠切除术中的对比:一项日本多中心随机对照临床试验的长期结果。
J Hepatobiliary Pancreat Sci. 2012 May;19(3):230-41. doi: 10.1007/s00534-011-0466-6.
7
Preservation of the pyloric ring has little value in surgery for pancreatic head cancer: a comparative study comparing three surgical procedures.保留幽门环在胰头癌手术中价值不大:三种手术方式的对比研究。
Ann Surg Oncol. 2012 Jan;19(1):176-83. doi: 10.1245/s10434-011-1901-2. Epub 2011 Jul 7.
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