Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
World J Surg. 2013 Aug;37(8):1778-81. doi: 10.1007/s00268-013-2039-0.
Lymph node metastasis is considered one of the most significant factors associated with postoperative prognosis in patients with pancreatic cancer. Some prospective studies found no significant differences in survival between patients who underwent pancreatic cancer surgery with extended lymphadenectomy and those who underwent surgery with standard lymphadenectomy. However, recent reports, such as those describing the significance of the metastatic to examined lymph node ratio, suggest the need for some degree of lymphadenectomy. This review describes the findings of published studies and discusses the usefulness of LN dissection in patients with pancreatic cancer.
淋巴结转移被认为是与胰腺癌患者术后预后最相关的因素之一。一些前瞻性研究发现,行扩大淋巴结清扫术和标准淋巴结清扫术的胰腺癌患者的生存无显著差异。然而,最近的一些报告,如描述转移至检查淋巴结比率的意义的报告,提示需要进行一定程度的淋巴结清扫。本文综述了已发表研究的结果,并讨论了 LN 解剖术在胰腺癌患者中的应用价值。