来自马纳尔湾韦达莱沿海水域的选定褐藻的抗菌潜力。
Antimicrobial potential of selected brown seaweeds from Vedalai coastal waters, Gulf of Mannar.
作者信息
Manivannan K, Karthikai Devi G, Anantharaman P, Balasubramanian T
机构信息
Centre of Advanced Study in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai, Tamilnadu, India.
出版信息
Asian Pac J Trop Biomed. 2011 Apr;1(2):114-20. doi: 10.1016/S2221-1691(11)60007-5.
OBJECTIVE
To evaluate the antimicrobial activity of Turbinaria conoides (T. conoides), Padina gymnospora (P. gymnospora) and Sargassum tenerrimum against human bacterial and fungal pathogens.
METHODS
The antimicrobial activities of the extracts against various organisms were tested by using disc diffusion method.
RESULTS
The methanol extract showed the better result than the other extracts. Whereas, the strong antibacterial inhibition was noted in methanol extracts of P. gymnospora against Bacillus subtilus (26.33±1.86) and the mild inhibition of ethanol extracts from T. conoides against Klebsiella pneumoniae (2.33±0.51). Acetone extraction of P. gymnospora had strong antifungal inhibition against Cryptococcus neoformans (23.00±1.78), and acetone extract of T. conoides had mild inhibition against Aspergillus niger (3.00±0.89).
CONCLUSIONS
The seven different solvent extracts of seaweeds used in the present study have shown significant bacterial action. Further, a detailed study on the principle compound in the seaweeds which is responsible for antimicrobial activity is still needed and it can be achieved by using advanced separation techniques.
目的
评估锥形叉珊藻、裸叶藻和柔弱马尾藻对人类细菌和真菌病原体的抗菌活性。
方法
采用纸片扩散法检测提取物对各种生物体的抗菌活性。
结果
甲醇提取物的效果优于其他提取物。其中，裸叶藻的甲醇提取物对枯草芽孢杆菌有较强的抗菌抑制作用（26.33±1.86），锥形叉珊藻的乙醇提取物对肺炎克雷伯菌有轻度抑制作用（2.33±0.51）。裸叶藻的丙酮提取物对新型隐球菌有较强的抗真菌抑制作用（23.00±1.78），锥形叉珊藻的丙酮提取物对黑曲霉有轻度抑制作用（3.00±0.89）。
结论
本研究中使用的七种不同溶剂提取的海藻提取物均显示出显著的抗菌作用。此外，仍需利用先进的分离技术对海藻中具有抗菌活性的主要化合物进行详细研究。
Zotero 插件