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乌拉胆碱和卡巴胆碱对十二指肠溃疡患者近端胃迷走神经切断术后五肽胃泌素刺激的胃酸分泌的影响;

Effect of urecholine and carbacholine on pentagastrin-stimulated gastric secretion after proximal gastric vagotomy in duodenal ulcer patients;

作者信息

Roland M, Berstad A, Liavåg I

出版信息

Scand J Gastroenterol. 1975;10(3):315-9.

PMID:1094533
Abstract

Six months after proximal gastric vagotomy gastric secretion was examined after infusion of pentagastrin, 15 mug/kg/hr, alone and in combination with urecholine, 60 mug/kg/hr, or carbacholine, 2 mug/kg/hr. There were no significant differences between mean acid outputs after the three types of stimulation. Pepsin outputs were significantly higher after pentagastrin plus carbacholine and pentagastrin plus urecholine than after pentagastrin alone. Urecholine and carbacholine increased pepsin secretion to a similar degree. Volume of gastric juice was significantly higher after simultaneous infusion of pentagastrin and urecholine than after pentagastrin alone or pentagastrin plus carbacholine.

摘要

在近端胃迷走神经切断术后六个月,在单独输注五肽胃泌素(15微克/千克/小时)以及与乌拉胆碱(60微克/千克/小时)或卡巴胆碱(2微克/千克/小时)联合输注后,对胃液分泌情况进行了检查。三种刺激类型后的平均胃酸分泌量之间无显著差异。五肽胃泌素加卡巴胆碱以及五肽胃泌素加乌拉胆碱后的胃蛋白酶分泌量显著高于单独使用五肽胃泌素后的分泌量。乌拉胆碱和卡巴胆碱对胃蛋白酶分泌的增加程度相似。同时输注五肽胃泌素和乌拉胆碱后的胃液量显著高于单独使用五肽胃泌素或五肽胃泌素加卡巴胆碱后的胃液量。

相似文献

1
Effect of urecholine and carbacholine on pentagastrin-stimulated gastric secretion after proximal gastric vagotomy in duodenal ulcer patients;乌拉胆碱和卡巴胆碱对十二指肠溃疡患者近端胃迷走神经切断术后五肽胃泌素刺激的胃酸分泌的影响;
Scand J Gastroenterol. 1975;10(3):315-9.
2
Decrease in gastric secretion during the first three months after proximal gastric vagotomy in duodenal ulcer patients.十二指肠溃疡患者近端胃迷走神经切断术后头三个月胃液分泌减少。
Scand J Gastroenterol. 1975;10(4):363-7.
3
Effect of carbacholine and urecholine on pentagastrin-stimulated gastric secretion in healthy subjects.卡巴胆碱和乌拉胆碱对健康受试者五肽胃泌素刺激的胃酸分泌的影响。
Scand J Gastroenterol. 1975;10(4):357-62.
4
Gastric secretory response to graded doses of pentagastrin alone or in combination with carbacholine in unoperated duodenal ulcer patients.未接受手术的十二指肠溃疡患者对不同剂量的五肽胃泌素单独或与卡巴胆碱联合使用的胃分泌反应。
Scand J Gastroenterol. 1975;10(6):603-8.
5
Acid and pepsin secretion in duodenal ulcer patients in response to graded doses of pentagastrin or pentagastrin and carbacholine before and after proximal gastric vagotomy.十二指肠溃疡患者在近端胃迷走神经切断术前、后对不同剂量的五肽胃泌素或五肽胃泌素与卡巴胆碱的胃酸和胃蛋白酶分泌情况。
Scand J Gastroenterol. 1974;9(6):511-8.
6
A secretory and histological study of the stomach before and after truncal vagotomy and pyloroplasty in duodenal ulcer patients.十二指肠溃疡患者行迷走神经干切断术和幽门成形术前后胃的分泌及组织学研究。
Scand J Gastroenterol. 1976;11(1):65-71.
7
The effect of carbachol and pentagastrin on the gastric secretion of acid pepsin, and intrinsic factor (IF) in man.卡巴胆碱和五肽胃泌素对人体胃酸、胃蛋白酶及内因子分泌的影响。
Scand J Gastroenterol. 1975;10(1):55-8.
8
The effect of atropine and vagotomy on the secretion of gastric intrinsic factor (IF) in man.阿托品和迷走神经切断术对人体胃内因子(IF)分泌的影响。
Scand J Gastroenterol. 1975;10(1):59-64.
9
Gastric secretory response to different doses of carbachol and pentagastrin in man.人对不同剂量卡巴胆碱和五肽胃泌素的胃分泌反应。
Scand J Gastroenterol. 1976;11(4):421-5.
10
Effect of cimetidine on stimulated gastric secretion and serum gastrin in the dog.西咪替丁对犬胃分泌及血清胃泌素的影响。
Am J Gastroenterol. 1978 Nov;70(5):437-47.

引用本文的文献

1
Effects of fundic vagotomy and cholinergic replacement on pentagastrin dose responsive gastric acid and pepsin secretion in man.胃底迷走神经切断术及胆碱能替代对人五肽胃泌素剂量依赖性胃酸和胃蛋白酶分泌的影响。
Gut. 1982 Aug;23(8):675-82. doi: 10.1136/gut.23.8.675.
2
Effect of bethanechol on gastric acid secretion and serum gastrin concentration after proximal gastric vagotomy.胃近端迷走神经切断术后氨甲酰甲胆碱对胃酸分泌及血清胃泌素浓度的影响。
Ann Surg. 1982 Jul;196(1):14-7. doi: 10.1097/00000658-198207000-00003.
3
Gastric secretory and motility studies in chronic chagasic patients.
慢性恰加斯病患者的胃分泌及运动研究。
Am J Dig Dis. 1977 Jul;22(7):618-22. doi: 10.1007/BF01073080.
4
Long-term effects of highly selective vagotomy (HSV) in dogs on acid and pepsin secretion.犬高选择性迷走神经切断术(HSV)对胃酸和胃蛋白酶分泌的长期影响。
Am J Dig Dis. 1977 Feb;22(2):81-95. doi: 10.1007/BF01072948.