Bergegårdh S, Olbe L
Scand J Gastroenterol. 1975;10(2):171-6.
Gastric acid secretion under basal conditions and in response to graded balloon distension (50 ml, 100 ml, 150 ml) of the antrum was determined in healthy subjects and in peptic ulcer patients. In patients with a quiescent duodenal ulcer or a gastric ulcer antrum distension produced slight acid responses. The acid response to antrum distension was of quantitative importance only in patients with an active duodenal ulcer, amounting to 35 percent of the maximal acid response to pentagastrin. The healthy subjects did not respond with acid secretion to antrum distension. The pH of the gastric contents in the present series was 1.8-3.0, being lowest in patients with an active duodenal ulcer. Thus, the acid secretory effect of mechanical stimulation of the antrum seems qualitatively different in healthy subjects and ulcer patients, with a marked acid response in patients with an active duodenal ulcer.
在健康受试者和消化性溃疡患者中，测定了基础状态下以及胃窦分级球囊扩张（50毫升、100毫升、150毫升）时的胃酸分泌情况。在十二指肠溃疡静止期或胃溃疡患者中，胃窦扩张引起的胃酸反应轻微。胃窦扩张引起的胃酸反应仅在活动性十二指肠溃疡患者中具有定量意义，占对五肽胃泌素最大胃酸反应的35%。健康受试者对胃窦扩张无胃酸分泌反应。本系列研究中胃内容物的pH值为1.8 - 3.0，在活动性十二指肠溃疡患者中最低。因此，胃窦机械刺激的胃酸分泌效应在健康受试者和溃疡患者中似乎存在质的差异，活动性十二指肠溃疡患者有明显的胃酸反应。
