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Use of biomarkers for diagnosis and management of traumatic brain injury patients.生物标志物在创伤性脑损伤患者诊断与管理中的应用。
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Prevalence of comorbidity and its association with traumatic brain injury and outcomes in older adults.老年人共病的患病率及其与创伤性脑损伤和预后的关联。
Res Gerontol Nurs. 2012 Jan;5(1):17-24. doi: 10.3928/19404921-20111206-02. Epub 2011 Dec 14.
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Elevated levels of serum glial fibrillary acidic protein breakdown products in mild and moderate traumatic brain injury are associated with intracranial lesions and neurosurgical intervention.血清神经胶质纤维酸性蛋白降解产物水平升高与轻度和中度创伤性脑损伤的颅内病变和神经外科干预有关。
Ann Emerg Med. 2012 Jun;59(6):471-83. doi: 10.1016/j.annemergmed.2011.08.021. Epub 2011 Nov 8.
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Rates of major depressive disorder and clinical outcomes following traumatic brain injury.颅脑损伤后重度抑郁障碍的发生率及临床结局。
JAMA. 2010 May 19;303(19):1938-45. doi: 10.1001/jama.2010.599.
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Serum S100B protein in early management of patients after mild traumatic brain injury.血清S100B蛋白在轻度创伤性脑损伤患者早期管理中的作用
Eur J Neurol. 2009 Oct;16(10):1112-7. doi: 10.1111/j.1468-1331.2009.02653.x. Epub 2009 May 12.
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Predicting outcome after severe traumatic brain injury using the serum S100B biomarker: results using a single (24h) time-point.使用血清S100B生物标志物预测重度创伤性脑损伤后的结果:单时间点(24小时)的结果
Resuscitation. 2009 Mar;80(3):341-5. doi: 10.1016/j.resuscitation.2008.11.021. Epub 2009 Jan 15.
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Clinical policy: neuroimaging and decisionmaking in adult mild traumatic brain injury in the acute setting.临床政策:急性成人轻度创伤性脑损伤的神经影像学检查与决策制定
Ann Emerg Med. 2008 Dec;52(6):714-48. doi: 10.1016/j.annemergmed.2008.08.021.
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Depression in the elderly after traumatic brain injury: a systematic review.创伤性脑损伤后老年人的抑郁:一项系统综述。
Brain Inj. 2008 May;22(5):375-80. doi: 10.1080/02699050802001492.
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Serum biomarker concentrations and outcome after pediatric traumatic brain injury.小儿创伤性脑损伤后的血清生物标志物浓度与预后
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10
Traumatic brain injury and delayed sequelae: a review--traumatic brain injury and mild traumatic brain injury (concussion) are precursors to later-onset brain disorders, including early-onset dementia.创伤性脑损伤及其迟发性后遗症:综述——创伤性脑损伤和轻度创伤性脑损伤(脑震荡)是包括早发性痴呆在内的迟发性脑部疾病的先兆。
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老年人群中的轻度创伤性脑损伤

Mild Traumatic Brain Injury among the Geriatric Population.

作者信息

Papa Linda, Mendes Matthew E, Braga Carolina F

机构信息

Department of Emergency Medicine, Orlando Regional Medical Center, Medical Education, Building, 86 West Underwood Street, S-200, Orlando, FL 32806, USA.

出版信息

Curr Transl Geriatr Exp Gerontol Rep. 2012 Sep 1;1(3):135-142. doi: 10.1007/s13670-012-0019-0.

DOI:10.1007/s13670-012-0019-0
PMID:23589783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3625036/
Abstract

Mild traumatic brain injury (TBI) is an unfortunately common occurrence in the elderly. With the growing population of older adults in the United States and globally, strategies that reduce the risk of becoming injured need to be developed, and diagnostic tools and treatments that may benefit this group need to be explored. Particular attention needs to be given to polypharmacy, drug interactions, the use of anticoagulants, safety issues in the living environment, elder abuse, and alcohol consumption. Low-mechanism falls should prompt health care providers to consider the possibility of head injury in elderly patients. Early and tailored management of our seniors following a mild TBI can provide them with the best possible quality of life. This review will discuss the current literature on mild TBI in the older adult, address gaps in research, and discuss the implications for future care of the older TBI patient.

摘要

轻度创伤性脑损伤(TBI)在老年人中是一种不幸常见的情况。随着美国及全球老年人口的不断增加,需要制定降低受伤风险的策略,并探索可能使这一群体受益的诊断工具和治疗方法。需要特别关注多重用药、药物相互作用、抗凝剂的使用、生活环境中的安全问题、虐待老人以及饮酒情况。低机制跌倒应促使医疗保健提供者考虑老年患者头部受伤的可能性。对轻度TBI后的老年人进行早期且量身定制的管理可为他们提供尽可能最佳的生活质量。本综述将讨论关于老年人轻度TBI的当前文献,阐述研究中的差距,并讨论对老年TBI患者未来护理的影响。