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变革的推动者:西澳大利亚州患者血液管理计划(WA PBMP)、世界卫生大会(WHA)和血液安全与供应咨询委员会(ACBSA)。

Drivers for change: Western Australia Patient Blood Management Program (WA PBMP), World Health Assembly (WHA) and Advisory Committee on Blood Safety and Availability (ACBSA).

机构信息

Patient Blood Management Program Team, Office of the Chief Medical Officer, Western Australia Department of Health, Perth, Western Australia, Australia.

出版信息

Best Pract Res Clin Anaesthesiol. 2013 Mar;27(1):43-58. doi: 10.1016/j.bpa.2012.12.007.

Abstract

Patient blood management is now high on national and international health-system agendas. Serious supply challenges as a result of changing population dynamics, escalating cost of blood, ongoing safety challenges and questions about transfusion efficacy and outcomes are necessitating change in transfusion practice. Numerous initiatives are underway to bring about change, including the institution of comprehensive patient blood management programmes. In 2008, the Western Australia Department of Health initiated a 5-year project to implement a comprehensive health-system-wide Patient Blood Management Program with the aim of improving patient outcomes while reducing costs. Clinically, the Program was structured on the three pillars of patient blood management, namely (1) optimising the patient's own red cell mass, (2) minimising blood loss and (3) harnessing and optimising the patient-specific anaemia reserve. It employs multiple strategies to bring about a cultural change from a blood-product focus to a patient focus. This Program was undertaken in a State that already had one of the lowest red blood cell issuance rates per 1000 population in the developed world (30.47 red blood cell units per 1000 population). The Program identified reasons and drivers for practice change. From financial years 2008-09 to 2011-12, issuance has progressively decreased in Western Australia to 27.54 units per 1000. During the same years, despite increasing activity, total issuance of red blood cells to the entire State decreased from 70,103 units to 65,742. Nationally and internationally, other initiatives are underway to bring about change and implement patient blood management. The World Health Assembly in May 2010 adopted resolution WHA63.12 endorsing patient blood management and its three-pillar application. The United States Advisory Committee on Blood Safety and Availability met in 2011 to consider the implications of this resolution and its implementation.

摘要

患者血液管理现在是国家和国际卫生系统议程上的重点。由于人口动态变化、血液成本不断上升、持续存在的安全挑战以及对输血效果和结果的质疑,导致输血实践需要改变。正在采取许多举措来实现这一转变,包括建立全面的患者血液管理计划。2008 年,西澳大利亚州卫生部启动了一个为期 5 年的项目,旨在实施一项全面的卫生系统范围内的患者血液管理计划,以改善患者的治疗效果并降低成本。从临床角度来看,该计划基于患者血液管理的三个支柱构建,即(1)优化患者自身的红细胞量,(2)减少失血,以及(3)利用和优化患者特有的贫血储备。它采用多种策略来实现从以血液制品为中心到以患者为中心的文化转变。该计划是在一个州进行的,该州已经是发达国家中每千人红细胞发放率最低的州之一(每千人发放 30.47 个红细胞单位)。该计划确定了实践改变的原因和驱动因素。从 2008-09 财政年度到 2011-12 财政年度,西澳大利亚州的发放量逐渐减少到每千人 27.54 个单位。在同期,尽管活动量增加,但向全州发放的红细胞总量从 70103 单位减少到 65742 单位。在国家和国际层面,其他旨在实现改变和实施患者血液管理的举措正在进行中。世界卫生大会在 2010 年 5 月通过了 WHA63.12 号决议,支持患者血液管理及其三支柱应用。美国血液安全和可用性咨询委员会于 2011 年举行会议,审议该决议及其实施的影响。

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