Naz Rabia, Bano Asghari
Department of Plant Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Asian Pac J Trop Biomed. 2012 Dec;2(12):944-7. doi: 10.1016/S2221-1691(13)60004-0.
To investigate the in vitro antimicrobial activities of the leaf extract in different solvents viz., methanol, ethanol and water extracts of the selected plant Ricinus communis.
Agar well diffusion method and agar tube dilution method were carried out to perform the antibacterial and antifungal activity of methanol, ethanol and aqueous extracts.
Methanol leaf extracts were found to be more active against Gram positive bacteria (Bacillus subtilis: ATCC 6059 and Staphylococcus aureus: ATCC 6538) as well as Gram negative bacteria (Pseudomonas aeruginosa: ATCC 7221 and Klebsiella pneumoniae) than ethanol and aqueous leaf extracts. Antifungal activity of methanol and aqueous leaf extracts were also carried out against selected fungal strains as Aspergillus fumigatus and Aspergillus flavus. Methanolic as well as aqueous leaf extracts of Ricinus communis were effective in inhibiting the fungal growth.
The efficient antibacterial and antifungal activity of Ricinus communis from the present investigation revealed that the methanol leaf extracts of the selected plant have significant potential to inhibit the growth of pathogenic bacterial and fungal strains than ethanol and aqueous leaf extracts.
研究蓖麻叶提取物在不同溶剂(即甲醇、乙醇和水提取物)中的体外抗菌活性。
采用琼脂扩散法和琼脂试管稀释法进行甲醇、乙醇和水提取物的抗菌和抗真菌活性实验。
发现甲醇叶提取物对革兰氏阳性菌(枯草芽孢杆菌:ATCC 6059和金黄色葡萄球菌:ATCC 6538)以及革兰氏阴性菌(铜绿假单胞菌:ATCC 7221和肺炎克雷伯菌)的活性比乙醇和水叶提取物更强。还对甲醇和水叶提取物针对烟曲霉和黄曲霉等选定真菌菌株进行了抗真菌活性实验。蓖麻叶的甲醇提取物和水提取物均能有效抑制真菌生长。
本次研究中蓖麻的高效抗菌和抗真菌活性表明,所选植物的甲醇叶提取物比乙醇和水叶提取物具有更显著的抑制致病细菌和真菌菌株生长的潜力。