乙哌立松对猫闰绍细胞的作用。

Effects of Eperisone on Renshaw cells of cats.

作者信息

Kato M, Yang Y H

机构信息

Department of Physiology, Hokkaido University School of Medicine, Sapporo, Japan.

出版信息

Neurosci Lett. 1990 May 4;112(2-3):246-50. doi: 10.1016/0304-3940(90)90211-q.

DOI:10.1016/0304-3940(90)90211-q

PMID:2359523

Abstract

Actions of Eperisone (4'-ethyl-2-methyl-3-piperidinopropiophenone; EMPP) on Renshaw cells were investigated on spinal cats. The characteristic high-frequency discharges of Renshaw cells within 20 ms following antidromic ventral root stimulation were depressed while the later responses which follow the earlier responses for 80 ms were enhanced following administration of EMPP. These effects suggest that EMPP has differential effects on nicotinic acetylcholine receptors of the Renshaw cells.

摘要

在脊髓猫上研究了乙哌立松（4'-乙基-2-甲基-3-哌啶基丙酰苯；EMPP）对闰绍细胞的作用。在逆向刺激腹根后20毫秒内闰绍细胞的特征性高频放电受到抑制，而在给予EMPP后，跟随早期反应80毫秒的后期反应增强。这些效应表明，EMPP对闰绍细胞的烟碱型乙酰胆碱受体有不同的作用。