Department of Ophthalmology, People's Hospital, Peking University; Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing 100044, China.
Chin Med J (Engl). 2013;126(8):1430-5.
Contrast sensitivity (CS) testing can detect differences in functional vision and is highly correlated with visual performance. This study was designed to investigate the association between CS and the grading score using the lens opacities classification system (LOCS) III as well as the association between CS and visual acuity (VA) in nuclear or cortical age-related cataract (ARC) patients.
A total of 270 eyes with ARC and 30 control eyes were divided into nuclear opacity (NO), nuclear color (NC), cortical cataract (C) based on LOCS III. The CS values measured at all spatial frequencies under photopic and glare conditions that resulted in contrast sensitivity function (CSF) were evaluated, and LogMAR VA was tested with the Early Treatment Diabetic Retinopathy Study (ETDRS) chart. The correlation between CSF and LOCS III grading scores, and between CSF and LogMAR VA were analyzed.
Compared to the controls, CSF of the nuclear or cortical ARC significantly declined. There are significant correlation between CSF and LogMAR VA, and between CSF and LOCS III grading scores. Compared to the VA, a stronger correlation existed between CSF and LOCS III grading score than that of LogMAR VA and LOCS III grading score. CS at some spatial frequencies is significantly influenced with LOCS III grading score.
CSF significantly declined with the increasing ARC grading scores. Comparing to VA, CSF reflected the severity of cataract more comprehensively. CS at low spatial frequency is significantly influenced by ARC. Therefore, CS is more precise than VA in assessing the visual function of ARC patients.
对比敏感度 (CS) 测试可以检测功能视力的差异，并且与视觉性能高度相关。本研究旨在探讨 CS 与 Lens Opacities Classification System III (LOCS III) 分级评分之间的关系，以及 CS 与核性或皮质性年龄相关性白内障 (ARC) 患者视力 (VA) 之间的关系。
共纳入 270 只 ARC 眼和 30 只对照眼，根据 LOCS III 将其分为核性混浊 (NO)、核性颜色 (NC) 和皮质性白内障 (C)。评估在明适应和眩光条件下所有空间频率下的 CS 值，使用早期糖尿病视网膜病变治疗研究 (ETDRS) 图表测试 LogMAR VA。分析 CSF 与 LOCS III 分级评分之间的相关性，以及 CSF 与 LogMAR VA 之间的相关性。
与对照组相比，核性或皮质性 ARC 的 CS 显著下降。CSF 与 LogMAR VA 之间以及与 LOCS III 分级评分之间均存在显著相关性。与 VA 相比，CSF 与 LOCS III 分级评分之间的相关性强于 LogMAR VA 与 LOCS III 分级评分之间的相关性。某些空间频率的 CS 明显受到 LOCS III 分级评分的影响。
CSF 随着 ARC 分级评分的增加而显著下降。与 VA 相比，CSF 更全面地反映了白内障的严重程度。ARC 对低空间频率的 CS 有明显影响。因此，CS 比 VA 更能准确评估 ARC 患者的视觉功能。
