Chylack L T, Jakubicz G, Rosner B, Khu P, Libman J, Wolfe J K, Padhye N, Friend J
Center for Clinical Cataract Research, Boston, Massachusetts 02115.
J Cataract Refract Surg. 1993 May;19(3):399-404. doi: 10.1016/s0886-3350(13)80313-6.
In a population of 188 nondiabetic patients with early cataracts or nuclear brunescence, we assessed the degree to which contrast sensitivity function (CSF) provided more information about a patient's visual disability than high contrast visual acuity measurements. Data collected included LOCS II cataract classification, Bailey-Lovie visual acuity (LogMAR score), Lotmar interferometric visual acuity (LI VA), and distance contrast sensitivity function (CSF) using the Vistech 6500. Generalized least squares regression models in which CS was the dependent variable and either LogMAR score or LI VA was among the independent variables were used to ascertain whether CSF provided additional information about visual disability to that provided by LogMAR score or LI VA. Contrast sensitivity function was decreased only by nuclear opalescence at high frequencies (12 to 18 cpd); for all other cataract types and nuclear color, CSF testing provided no more information about cataract-related visual loss than LI VA or LogMAR score. Measurement of CSF using the Vistech 6500 system in patients with early cataracts provides information on visual dysfunction beyond that provided by LogMAR score or LI VA only in patients with nuclear opalescence, and that may not be clinically significant.
在188例患有早期白内障或核性混浊的非糖尿病患者群体中，我们评估了与高对比度视力测量相比，对比敏感度功能（CSF）在多大程度上能提供更多关于患者视力残疾的信息。收集的数据包括LOCS II白内障分级、贝利-洛维视力（LogMAR评分）、洛特马干涉视力（LI VA）以及使用Vistech 6500测量的距离对比敏感度功能（CSF）。以CS为因变量且LogMAR评分或LI VA为自变量之一的广义最小二乘回归模型，用于确定CSF是否能提供除LogMAR评分或LI VA所提供信息之外的关于视力残疾的额外信息。仅在高频（12至18周/度）时，对比敏感度功能会因核性混浊而降低；对于所有其他白内障类型和核颜色，CSF测试所提供的关于白内障相关视力丧失的信息并不比LI VA或LogMAR评分更多。仅在患有核性混浊的患者中，使用Vistech 6500系统测量CSF能提供超出LogMAR评分或LI VA所提供的关于视力功能障碍的信息，且这可能在临床上并不显著。
