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2米连续波激光在经尿道前列腺汽化切除术中应用的临床研究

Clinical study on the application of a 2-m continuous wave laser in transurethral vaporesection of the prostate.

作者信息

Xu Yong, Sun Dongchong, Wei Zhitao, Hong Baofa, Yang Yong

机构信息

Department of Urology, PLA General Hospital, Beijing 100056, P.R. China.

出版信息

Exp Ther Med. 2013 Apr;5(4):1097-1100. doi: 10.3892/etm.2013.951. Epub 2013 Feb 5.

Abstract

The present study aimed to evaluate the method and clinical effects of transurethral dividing vaporesection of the prostate in the management of benign prostatic hyperplasia (BPH) using the RevoIix 70 W 2-m continuous wave (cw) laser. A total of 155 BPH patients were treated transurethrally under epidural or sacral anesthesia using the dividing vaporesection technique. Of these, 80 had a prostate volume of ≤80 ml and 75 had a prostate volume of >80 ml. Pre- and post-operative data were evaluated for prostate-specific antigens (PSAs), post-void residual volume (PVR), maximum urinary flow rate (Qmax), International Prostate Symptom Score (IPSS) and quality of life (QoL). Statistical analyses were performed using the SPSS 16.0 software. Treatment effectiveness evaluations were also conducted. In the ≤80 ml prostate volume group, the mean PSA level decreased from 3.8±0.9 to 2.6±1.3 ng/ml. The PVR, mean Qmax, IPSS and QoL score improved significantly (P<0.05) in each group but no statistically significant difference was identified between the two groups. With a shorter surgery duration, safe use and high cutting efficiency and rapid vaporization ability, the 2-m laser vaporesection technique shows superiority compared to standard techniques in the treatment of BPH.

摘要

本研究旨在评估使用RevoIix 70W 2米连续波(cw)激光经尿道前列腺分割汽化切除术治疗良性前列腺增生(BPH)的方法及临床效果。共有155例BPH患者在硬膜外或骶管麻醉下采用经尿道分割汽化技术进行治疗。其中,80例患者前列腺体积≤80ml,75例患者前列腺体积>80ml。对术前和术后的前列腺特异性抗原(PSA)、残余尿量(PVR)、最大尿流率(Qmax)、国际前列腺症状评分(IPSS)和生活质量(QoL)数据进行评估。使用SPSS 16.0软件进行统计分析,并进行治疗效果评估。在前列腺体积≤80ml组中,平均PSA水平从3.8±0.9降至2.6±1.3ng/ml。每组的PVR、平均Qmax、IPSS和QoL评分均有显著改善(P<0.05),但两组之间未发现统计学上的显著差异。2米激光汽化切除术技术手术时间较短、使用安全、切割效率高且汽化迅速,在治疗BPH方面与标准技术相比具有优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca8e/3628398/e4900343c73f/ETM-05-04-1097-g00.jpg

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