冷冻精液质量和定时宫内授精对供精人工授精项目中妊娠率及子代性别的影响
Effects of cryopreserved semen quality and timed intrauterine insemination on pregnancy rate and gender of offspring in a donor insemination program.
作者信息
Sidhu R S, Sharma R K, Agarwal A
机构信息
Department of Urology, Cleveland Clinic Foundation, Ohio 44195, USA.
出版信息
J Assist Reprod Genet. 1997 Oct;14(9):531-7. doi: 10.1023/a:1021131511209.
PURPOSE
Our purpose was to study the relationship among cryopreserved donor semen quality, pregnancy rates, and preconception sex selection after intrauterine insemination.
METHODS
We reviewed the records of the 203 women in our donor insemination program from 1987 to 1994 who became pregnant after more than one insemination cycle and had no female-factor infertility. They were categorized according to the number of cycles required for pregnancy. Semen samples from 54 donors were analyzed before freezing and after thawing. Specimens resulting in pregnancy were compared to specimens from the same donor that did not. Semen characteristics were compared to gender of the child.
RESULTS
Two hundred fifty two-women became pregnant of the 422 who were enrolled. The pregnancy rate per cycle was 13%. Semen quality was not related to pregnancy outcome or offspring gender. However, more male children (101 vs 83) were born.
CONCLUSIONS
Semen characteristics in good-quality cryopreserved donor semen do not affect pregnancy rate or offspring gender.
目的
我们的目的是研究冷冻保存的供体精液质量、妊娠率和宫内授精后受孕前性别选择之间的关系。
方法
我们回顾了1987年至1994年在我们的供体授精项目中，经过一个以上授精周期后怀孕且无女性因素不孕的203名女性的记录。她们根据怀孕所需的周期数进行分类。对54名供体的精液样本在冷冻前和解冻后进行分析。将导致怀孕的样本与来自同一供体但未导致怀孕的样本进行比较。将精液特征与孩子的性别进行比较。
结果
在登记的422名女性中，有252名怀孕。每个周期的妊娠率为13%。精液质量与妊娠结局或后代性别无关。然而，出生的男婴更多（101名对83名）。
结论
优质冷冻保存的供体精液的精液特征不影响妊娠率或后代性别。
Zotero 插件