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针对初级保健中与自杀风险相关的筛查和治疗:美国预防服务工作组的系统评价。

Screening for and treatment of suicide risk relevant to primary care: a systematic review for the U.S. Preventive Services Task Force.

机构信息

Center for Health Research, Kaiser Permanente Northwest, Portland, OR 97227, USA.

出版信息

Ann Intern Med. 2013 May 21;158(10):741-54. doi: 10.7326/0003-4819-158-10-201305210-00642.

Abstract

BACKGROUND

In 2009, suicide accounted for 36 897 deaths in the United States.

PURPOSE

To review the accuracy of screening instruments and the efficacy and safety of screening for and treatment of suicide risk in populations and settings relevant to primary care.

DATA SOURCES

Citations from MEDLINE, PsycINFO, the Cochrane Central Register of Controlled Trials, and CINAHL (2002 to 17 July 2012); gray literature; and a surveillance search of MEDLINE for additional screening trials (July to December 2012).

STUDY SELECTION

Fair- or good-quality English-language studies that assessed the accuracy of screening instruments in primary care or similar populations and trials of suicide prevention interventions in primary or mental health care settings.

DATA EXTRACTION

One investigator abstracted data; a second checked the abstraction. Two investigators rated study quality.

DATA SYNTHESIS

Evidence was insufficient to determine the benefits of screening in primary care populations; very limited evidence identified no serious harms. Minimal evidence suggested that screening tools can identify some adults at increased risk for suicide in primary care, but accuracy was lower in studies of older adults. Minimal evidence limited to high-risk populations suggested poor performance of screening instruments in adolescents. Trial evidence showed that psychotherapy reduced suicide attempts in high-risk adults but not adolescents. Most trials were insufficiently powered to detect effects on deaths.

LIMITATION

Treatment evidence was derived from high-risk rather than screening-detected populations. Evidence relevant to adolescents, older adults, and racial or ethnic minorities was limited.

CONCLUSION

Primary care-feasible screening tools might help to identify some adults at increased risk for suicide but have limited ability to detect suicide risk in adolescents. Psychotherapy may reduce suicide attempts in some high-risk adults, but effective interventions for high-risk adolescents are not yet proven.

PRIMARY FUNDING SOURCE

Agency for Healthcare Research and Quality.

摘要

背景

2009 年,美国有 36897 人自杀身亡。

目的

综述在与初级保健相关的人群和环境中,自杀风险筛查工具的准确性,以及筛查和治疗自杀风险的效果和安全性。

数据来源

从 MEDLINE、PsycINFO、Cochrane 对照试验中心注册库和 CINAHL(2002 年至 2012 年 7 月 17 日)中检索文献;灰色文献;以及对 MEDLINE 中筛查试验的监测检索(2012 年 7 月至 12 月)。

研究选择

评估初级保健或类似人群中筛查工具准确性的,或评估初级或精神保健环境中自杀预防干预措施的效果和安全性的高质量、英文学术研究。

数据提取

一名研究者提取数据,另一名研究者复核。两名研究者评价研究质量。

数据综合

证据不足以确定初级保健人群中筛查的益处;非常有限的证据未发现严重危害。少量证据表明,筛查工具可以识别初级保健中一些自杀风险增加的成年人,但在老年人群体中研究的准确性较低。仅在高危人群中获得的少量证据表明,筛查工具在青少年中表现不佳。试验证据表明,心理治疗减少了高危成年人的自杀企图,但没有减少青少年的自杀企图。大多数试验的效力不足以检测对死亡的影响。

局限性

治疗证据来自高危人群,而不是筛查检出的人群。与青少年、老年人以及种族或少数民族相关的证据有限。

结论

初级保健可行的筛查工具可能有助于识别一些自杀风险增加的成年人,但识别青少年自杀风险的能力有限。心理治疗可能减少一些高危成年人的自杀企图,但尚未证明对高危青少年有效的干预措施。

主要资金来源

美国医疗保健研究与质量局。

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