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[利用血清中γ-谷氨酰转肽酶活性的测定来确定酒精解毒治疗的成功与否(作者译)]

[Use of the measurement of gamma-glutamyltranspeptidase activity in serum to determine the success of cures for alcohol detoxification (author's transl)].

作者信息

Lamy J, Baglin M C, Ferrant J P, Weill J

出版信息

Clin Chim Acta. 1975 Apr 2;60(1):103-7. doi: 10.1016/0009-8981(75)90186-2.

Abstract

44 patients were studied during a 2-year period following a cure for alcohol detoxification. 29 patients (group A) did not start drinking again while 15 relapsed less than one year after their cure (group R). The average gamma GT activity (m) in mU per ml serum was, in group A, 148 (standard deviation, S.D. 184) at the beginning of the cure, 21 (S.D. 14) after one year and 19 (S.D. 13) after 2 years. During the same period there was no significant decrease in group R (cure: m 140, S.D. 161: 1 year: m 166, S.D. 164; 2 years: m 162, S.D. 163). On the other hand, all the subjects of group A who had a high gamma GT activity (greater than 29 mU/ml) at the start of the cure showed a decrease after one year.

摘要

在酒精脱瘾治愈后的两年期间对44名患者进行了研究。29名患者(A组)未再次饮酒,而15名患者在治愈后不到一年复发(R组)。A组血清中每毫升毫国际单位(mU)的平均γ-谷氨酰转移酶(gamma GT)活性(m)在治疗开始时为148(标准差,S.D. 184),一年后为21(S.D. 14),两年后为19(S.D. 13)。在同一时期,R组没有显著下降(治疗时:m 140,S.D. 161;一年时:m 166,S.D. 164;两年时:m 162,S.D. 163)。另一方面,A组中所有在治疗开始时γ-谷氨酰转移酶活性高(大于29 mU/ml)的受试者在一年后均出现下降。

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