睡眠模式与单相抑郁风险：综述。
Sleep patterns and the risk for unipolar depression: a review.
机构信息
Attention, Behavior and Sleep Laboratory, Douglas Mental Health University Institute, Montréal; McGill University, Montréal, Quebec, Canada.
出版信息
Nat Sci Sleep. 2012 May 29;4:63-71. doi: 10.2147/NSS.S23490. Print 2012.
Abstract
Psychological disorders, particularly mood disorders, such as unipolar depression, are often accompanied by comorbid sleep disturbances, such as insomnia, restless sleep, and restricted sleep duration. The nature of the relationship between unipolar depression and these sleep disturbances remains unclear, as sleep disturbance may be a risk factor for development, an initial manifestation of the disorder, or a comorbid condition affected by similar mechanisms. Various studies have examined the impact of sleep deprivation on the presence of (or exacerbation of) depressive symptoms, and have examined longitudinal and concurrent associations between different sleep disturbances and unipolar depression. This review examines the evidence for sleep disturbances as a risk factor for the development and presence of depression, as well as examining common underlying mechanisms. Clinical implications pertaining to the comorbid nature of various sleep patterns and depression are considered.
摘要
心理障碍，特别是情绪障碍，如单相抑郁症，通常伴有并发的睡眠障碍，如失眠、睡眠不安和睡眠时间受限。单相抑郁症和这些睡眠障碍之间的关系性质尚不清楚，因为睡眠障碍可能是发展的风险因素、疾病的初始表现，或受相似机制影响的合并症。各种研究已经检查了睡眠剥夺对（或加重）抑郁症状的存在的影响，并检查了不同睡眠障碍与单相抑郁症之间的纵向和同期关联。本综述检查了睡眠障碍作为发展和出现抑郁症的风险因素的证据，并检查了常见的潜在机制。考虑了与各种睡眠模式和抑郁症共病性质相关的临床意义。
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