Yavari Zeinab, Esmaeeli Shooka, Paydary Koosha, Emamzadeh-Fard Sahra, Seyedalinaghi Seyedahmad, Rasoulinejad Mehrnaz
Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, Iran.
Asian Pac J Trop Biomed. 2013 Apr;3(4):334-6. doi: 10.1016/S2221-1691(13)60074-X.
To identify the frequency of syphilis among Iranian HIV-positive patients.
A cross-sectional study on the prevalence of syphilis and HIV co-infection among 450 patients diagnosed with HIV infection was conducted between 2004 and 2008 at Imam Khomeini hospital, Tehran, Iran. The lab tests including CD4 cell count, cerebrospinal fluid, veneral disease research laboratory (VDRL), fluorescent treponema antibody-absorption (FTA-Abs) and viral load were performed for all the patients. Data regarding medical history and their demographics were also collected.
Of all 450 HIV-positive patients, 24 (5.3%) had a positive VDRL test and only two men had a FTA-Abs positive test which means 0.45% of them had a definite co-infection of syphilis. 65.3% of the HIV-positive patients were injection drug users that the co-infection prevalence of them was 0.7%. We did not find any patient with neurosyphilis.
Considering the increasing prevalence of HIV and also extensive use of highly active antiretroviral therapy in developing nations, the diagnosis of syphilis should be timely established using screening tests among such patients.
确定伊朗HIV阳性患者中梅毒的感染率。
2004年至2008年期间，在伊朗德黑兰的伊玛目霍梅尼医院对450例确诊为HIV感染的患者进行了梅毒和HIV合并感染患病率的横断面研究。对所有患者进行了实验室检查，包括CD4细胞计数、脑脊液、性病研究实验室（VDRL）、荧光密螺旋体抗体吸收试验（FTA-Abs）和病毒载量检测。还收集了患者的病史和人口统计学数据。
在所有450例HIV阳性患者中，24例（5.3%）VDRL检测呈阳性，只有两名男性FTA-Abs检测呈阳性，这意味着他们中0.45%确诊合并梅毒感染。65.3%的HIV阳性患者为注射吸毒者，他们的合并感染率为0.7%。我们未发现任何神经梅毒患者。
考虑到HIV患病率不断上升以及发展中国家广泛使用高效抗逆转录病毒疗法，应通过筛查试验及时对这类患者进行梅毒诊断。
