Venojärvi Mika, Korkmaz Ayhan, Wasenius Niko, Manderoos Sirpa, Heinonen Olli J, Lindholm Harri, Aunola Sirkka, Eriksson Johan G, Atalay Mustafa
Institute of Biomedicine, Exercise Medicine, University of Eastern Finland, Kuopio, Finland.
Food Chem Toxicol. 2013 Nov;61:127-35. doi: 10.1016/j.fct.2013.04.015. Epub 2013 Apr 25.
Our aim was to determine whether 12 weeks' aerobic Nordic walking (NW) or resistance exercise training (RT) without diet-induced weight loss could decrease oxidative stress and atherogenic index of plasma (AIP), prevalence of metabolic syndrome (MetS) and MetS score in middle-aged men with impaired glucose regulation (IGR) (n=144. 54.5 ± 6.5 years). In addition, we compared effects of intervention between overweight and obese subgroups. Prevalence of MetS and AIP index decreased only in NW group and MetS score in both NW and RT groups but not in control group. The changes in AIP index correlated inversely with changes in plasma antioxidant capacity. The change in AIP index remained a significant independent predictor of the changes in MetS score after the model was adjusted for age, BMI and volume of exercise (MET h/week) in NW group. There were no changes in the other measured markers of oxidative stress and related cytokines (e.g. osteopontin and osteoprotegerin) in any of the groups. Nordic walking decreased prevalence of MetS and MetS score. Improved lipid profile remained a predictor of decreased MetS score only in NW group and it seems that Nordic walking has more beneficial effects on cardiovascular disease risks than RT training.
我们的目的是确定，在不通过节食减肥的情况下，进行为期12周的有氧越野行走（NW）或抗阻运动训练（RT）是否能降低糖调节受损（IGR）中年男性（n = 144，年龄54.5 ± 6.5岁）的氧化应激和血浆致动脉粥样化指数（AIP）、代谢综合征（MetS）患病率及MetS评分。此外，我们比较了超重和肥胖亚组之间的干预效果。MetS患病率和AIP指数仅在NW组下降，MetS评分在NW组和RT组均下降，而对照组未下降。AIP指数的变化与血浆抗氧化能力的变化呈负相关。在NW组中，在对年龄、体重指数和运动量（代谢当量小时/周）进行模型调整后，AIP指数的变化仍然是MetS评分变化的显著独立预测因素。任何一组中氧化应激和相关细胞因子（如骨桥蛋白和骨保护素）的其他测量指标均无变化。越野行走降低了MetS患病率和MetS评分。仅在NW组中，改善的血脂谱仍然是MetS评分降低的预测因素，而且似乎越野行走对心血管疾病风险的有益影响比RT训练更大。
