Suppr超能文献

蛋白质模型门户——蛋白质结构和模型信息的综合资源。

The Protein Model Portal--a comprehensive resource for protein structure and model information.

机构信息

Biozentrum University of Basel, Klingelbergstrasse 50-70, 4056 Basel, Switzerland.

出版信息

Database (Oxford). 2013 Apr 26;2013:bat031. doi: 10.1093/database/bat031. Print 2013.

Abstract

The Protein Model Portal (PMP) has been developed to foster effective use of 3D molecular models in biomedical research by providing convenient and comprehensive access to structural information for proteins. Both experimental structures and theoretical models for a given protein can be searched simultaneously and analyzed for structural variability. By providing a comprehensive view on structural information, PMP offers the opportunity to apply consistent assessment and validation criteria to the complete set of structural models available for proteins. PMP is an open project so that new methods developed by the community can contribute to PMP, for example, new modeling servers for creating homology models and model quality estimation servers for model validation. The accuracy of participating modeling servers is continuously evaluated by the Continuous Automated Model EvaluatiOn (CAMEO) project. The PMP offers a unique interface to visualize structural coverage of a protein combining both theoretical models and experimental structures, allowing straightforward assessment of the model quality and hence their utility. The portal is updated regularly and actively developed to include latest methods in the field of computational structural biology. Database URL: http://www.proteinmodelportal.org.

摘要

蛋白质模型门户(PMP)旨在通过为蛋白质的结构信息提供便捷且全面的访问,促进 3D 分子模型在生物医学研究中的有效应用。可以同时搜索给定蛋白质的实验结构和理论模型,并对其结构变异性进行分析。通过提供对结构信息的全面了解,PMP 提供了机会,可将一致的评估和验证标准应用于可用于蛋白质的整套结构模型。PMP 是一个开放项目,因此社区开发的新方法可以为 PMP 做出贡献,例如,用于创建同源模型的新建模服务器和用于模型验证的模型质量评估服务器。连续自动模型评估(CAMEO)项目不断评估参与建模服务器的准确性。PMP 提供了一个独特的界面,用于可视化蛋白质的结构覆盖范围,结合理论模型和实验结构,允许直接评估模型质量,从而评估其用途。该门户定期更新,并积极开发,以纳入计算结构生物学领域的最新方法。数据库 URL:http://www.proteinmodelportal.org。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ed7/3889916/cfe8cfe71bf9/bat031f1p.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验