ValiDichro：一个用于验证和控制蛋白质圆二色性光谱质量的网站。
ValiDichro: a website for validating and quality control of protein circular dichroism spectra.
机构信息
Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, UK.
出版信息
Nucleic Acids Res. 2013 Jul;41(Web Server issue):W417-21. doi: 10.1093/nar/gkt287. Epub 2013 Apr 26.
Abstract
Circular dichroism (CD) spectroscopy is widely used in structural biology as a technique for examining the structure, folding and conformational changes of proteins. A new server, ValiDichro, has been developed for checking the quality and validity of CD spectral data and metadata, both as an aid to data collection and processing and as a validation procedure for spectra to be included in publications. ValiDichro currently includes 25 tests for data completeness, consistency and quality. For each test that is done, not only is a validation report produced, but the user is also provided with suggestions for correcting or improving the data. The ValiDichro server is freely available at http://valispec.cryst.bbk.ac.uk/circularDichroism/ValiDichro/upload.html.
摘要
圆二色性（CD）光谱广泛应用于结构生物学领域，是一种用于研究蛋白质结构、折叠和构象变化的技术。为了检查 CD 光谱数据和元数据的质量和有效性，开发了一个名为 ValidiChro 的新服务器，它既是数据收集和处理的辅助工具，也是发表光谱数据的验证程序。ValidiChro 目前包括 25 种用于数据完整性、一致性和质量的测试。对于完成的每一项测试，不仅会生成验证报告，还会为用户提供纠正或改进数据的建议。ValidiChro 服务器可免费在 http://valispec.cryst.bbk.ac.uk/circularDichroism/ValiDichro/upload.html 获得。
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