Seijas Roberto, Ares Oscar, Catala Jordi, Alvarez-Diaz Pedro, Cusco Xavier, Cugat Ramon
Instituto de Ortopedia y Traumatologia, Fundacion García Cugat Hospital Quiron Barcelona, Spain.
J Orthop Surg (Hong Kong). 2013 Apr;21(1):10-4. doi: 10.1177/230949901302100105.
To evaluate the stages of patellar tendon graft remodelling using magnetic resonance imaging (MRI) after anterior cruciate ligament (ACL) reconstruction with or without platelet-rich plasma (PRP) injection.
98 patients aged 18 to 65 years with complete rupture of the ACL were randomised to undergo reconstruction with the autologous patellar tendon grafts with or without PRP injection. For the PRP group, 8 ml of PRP was obtained in the surgery room and was percutaneously injected into the suprapatellar joint after portal suture. MRI was obtained at months 4, 6, and 12. Remodelling stages of the grafts were classified as hypointense, mildly hyperintense, moderately hyperintense, severely hyperintense, and diffusely hyperintense by a radiologist blinded to treatment allocation.
More patients in the PRP group than controls attained higher stages of remodelling at month 4 (p=0.003), month 6 (p=0.0001), and month 12 (p=0.354).
PRP enabled faster remodelling of patellar tendon grafts.
使用磁共振成像（MRI）评估在有或无富血小板血浆（PRP）注射的情况下，前交叉韧带（ACL）重建术后髌腱移植物的重塑阶段。
98例年龄在18至65岁之间的ACL完全断裂患者被随机分为接受自体髌腱移植物重建且有或无PRP注射两组。对于PRP组，在手术室获取8 ml PRP，并在缝合切口后经皮注射入髌上关节。在第4、6和12个月时进行MRI检查。由对治疗分配不知情的放射科医生将移植物的重塑阶段分类为低信号、轻度高信号、中度高信号、重度高信号和弥漫性高信号。
在第4个月（p = 0.003）、第6个月（p = 0.0001）和第12个月（p = 0.354）时，PRP组比对照组有更多患者达到更高的重塑阶段。
PRP可使髌腱移植物更快地重塑。
